Effectiveness and tolerability of adjunctive brivaracetam in patients with focal seizures: Second interim analysis of 6-month data from a prospective observational study in Europe
Sign Up to like & getrecommendations! Published in 2020 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2020.106329
Abstract: Brivaracetam (BRV) is indicated for adjunctive treatment of focal (partial-onset) seizures with or without secondary generalisation in patients 4 years of age and older in the European Union (EU). An ongoing 12-month, prospective, non-interventional post-marketing… read more here.
Keywords: treatment; interim analysis; study; focal seizures ... See more keywords
Neuroprotective Effect of Brivaracetam and Perampanel Combination on Electrographic Seizures and Behavior Anomalies in Pentylenetetrazole-Kindled Mice
Sign Up to like & getrecommendations! Published in 2024 at "ACS Omega"
DOI: 10.1021/acsomega.4c00962
Abstract: Pentylenetetrazole (PTZ)-induced kindling is a broadly used experimental model to study the anticonvulsive potential of new and existing chemical moieties with the aim of discovering drugs hindering seizure progression and associated neurological comorbidities. In the… read more here.
Keywords: combination; kindled mice; brivaracetam; ptz ... See more keywords
Investigating clinical pharmacokinetics of brivaracetam by using a pharmacokinetic modeling approach
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-63903-1
Abstract: The development of technology and the processing speed of computing machines have facilitated the evaluation of advanced pharmacokinetic (PK) models, making modeling processes simple and faster. The present model aims to analyze the PK of… read more here.
Keywords: brivaracetam using; using pharmacokinetic; pharmacokinetics brivaracetam; investigating clinical ... See more keywords
The preclinical discovery and development of brivaracetam for the treatment of focal epilepsy
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2017.1366985
Abstract: ABSTRACT Introduction: Brivaracetam (BRV) is a new AED currently licensed for the adjunctive treatment of adult patients with focal epilepsies. It is a ligand of the ubiquitous synaptic vesicle glycoprotein 2A (SV2A). Areas covered: This… read more here.
Keywords: brivaracetam; preclinical discovery; treatment; brv ... See more keywords
Long-term efficacy, tolerability, and retention of brivaracetam in epilepsy treatment: A longitudinal multicenter study with up to 5 years of follow-up.
Sign Up to like & getrecommendations! Published in 2021 at "Epilepsia"
DOI: 10.1111/epi.17087
Abstract: OBJECTIVE This study was undertaken to evaluate the long-term efficacy, retention, and tolerability of add-on brivaracetam (BRV) in clinical practice. METHODS A multicenter, retrospective cohort study recruited all patients who initiated BRV between February and… read more here.
Keywords: epilepsy; term; long term; study ... See more keywords
Occurrence and genetic diversity of Blackcurrant reversion virus found on various cultivated and wild Ribes in Latvia
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DOI: 10.1111/ppa.12716
Abstract: A large-scale survey was carried out to assess the occurrence, natural host range and genetic diversity of Blackcurrant reversion virus (BRV) in cultivated and wild Ribes in Latvia using RT-PCR and sequence analyses of 3’… read more here.
Keywords: genetic diversity; occurrence; brv; diversity blackcurrant ... See more keywords
Mirror, Mirror on the Wall, Who’s the Fairest Third Generation Anti-Seizure Medication of All?
Sign Up to like & getrecommendations! Published in 2024 at "Epilepsy Currents"
DOI: 10.1177/15357597241232877
Abstract: A Real-World Comparison Among Third-Generation Antiseizure Medications: Results From the COMPARE Study Roberti R, Di Gennaro G, Anzellotti F, Arnaldi D, Belcastro V, Beretta S, Boero G, Bonanni P, Canafoglia L, D’Aniello A, Dainese F,… read more here.
Keywords: mirror; etiology; third generation; efficacy ... See more keywords
Brivaracetam: a novel antiepileptic drug for focal-onset seizures
Sign Up to like & getrecommendations! Published in 2018 at "Therapeutic Advances in Neurological Disorders"
DOI: 10.1177/1756285617742081
Abstract: Brivaracetam (BRV), the n-propyl analogue of levetiracetam (LEV), is the latest antiepileptic drug (AED) to be licensed in Europe and the USA for the adjunctive treatment of focal-onset seizures with or without secondary generalization in… read more here.
Keywords: drug; focal onset; onset seizures; brv ... See more keywords
Risk factors for bovine rotavirus infection and genotyping of bovine rotavirus in diarrheic calves in Bangladesh
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DOI: 10.1371/journal.pone.0264577
Abstract: Bovine rotavirus (BRV) is considered the leading cause of calf diarrhea worldwide, including Bangladesh. In this study we aimed to identify risk factors for BRV infection and determine the G and P genotypes of BRV… read more here.
Keywords: infection; bovine rotavirus; brv; risk factors ... See more keywords
MicroRNA Profile of MA-104 Cell Line Associated With the Pathogenesis of Bovine Rotavirus Strain Circulated in Chinese Calves
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.854348
Abstract: Bovine rotavirus (BRV) causes massive economic losses in the livestock industry worldwide. Elucidating the pathogenesis of BRV would help in the development of more effective measures to control BRV infection. The MA-104 cell line is… read more here.
Keywords: mml; bovine rotavirus; brv; mml mir ... See more keywords
De Novo Transcriptome Analysis of R. nigrum cv. Aldoniai in Response to Blackcurrant Reversion Virus Infection
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179560
Abstract: The most damaging pathogen in blackcurrant plantations is mite-transmitted blackcurrant reversion virus (BRV). Some Ribes species have an encoded genetic resistance to BRV. We performed RNA sequencing analysis of BRV-resistant blackcurrant cv. Aldoniai to evaluate… read more here.
Keywords: reversion virus; brv; analysis; blackcurrant reversion ... See more keywords