Insertion of scFv into the hinge domain of full-length IgG1 monoclonal antibody results in tetravalent bispecific molecule with robust properties
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DOI: 10.1080/19420862.2016.1270492
Abstract: ABSTRACT By simultaneous binding two disease mediators, bispecific antibodies offer the opportunity to broaden the utility of antibody-based therapies. Herein, we describe the design and characterization of Bs4Ab, an innovative and generic bispecific tetravalent antibody… read more here.
Keywords: full length; bs4ab; antibody; igg1 monoclonal ... See more keywords