A novel T cell-redirecting anti-GPRC5D × CD3 bispecific antibody with potent antitumor activity in multiple myeloma preclinical models
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DOI: 10.1038/s41598-024-55143-0
Abstract: G-protein-coupled receptor class 5 member D (GPRC5D) is detected in malignant plasma cells in approximately 90% of patients diagnosed with multiple myeloma (MM). Here, we constructed BsAb5003, a novel humanized bispecific monoclonal antibody targeting CD3… read more here.
Keywords: multiple myeloma; bsab5003; cell redirecting; antibody ... See more keywords