Bach1-induced suppression of angiogenesis is dependent on the BTB domain
Sign Up to like & getrecommendations! Published in 2020 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.102617
Abstract: The transcription factor Bach1 impairs angiogenesis after ischemic injury by suppressing Wnt/β-catenin signaling; however, the specific domains responsible for the anti-angiogenic effects of Bach1 remain unclear. This study determined the role of the BTB domain… read more here.
Keywords: btb; angiogenesis; domain bach1; bach1 ... See more keywords
Bi-allelic c.181_183delTGT in BTB domain of KLHL7 is associated with overlapping phenotypes of Crisponi/CISS1-like and Bohring-Opitz like syndrome.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medical genetics"
DOI: 10.1016/j.ejmg.2018.08.009
Abstract: Biallelic pathogenic variants in KLHL7 are known to result in Crisponi syndrome (CS)/cold-induced sweating syndrome type 1 (CISS1) like phenotype and Bohring-Opitz-like syndrome. In this report, a trio whole-exome sequencing (WES) was performed in proband… read more here.
Keywords: bohring opitz; ciss1 like; btb domain; klhl7 ... See more keywords
Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1.
Sign Up to like & getrecommendations! Published in 2021 at "Structure"
DOI: 10.1016/j.str.2021.06.005
Abstract: The repurposing of structurally conserved protein domains in different functional contexts is thought to be a driving force in the evolution of complex protein interaction networks. The BTB/POZ domain is such a versatile binding module… read more here.
Keywords: zinc finger; btb domain; domain;
Zinc finger and BTB domain-containing protein 46 is essential for survival and proliferation of acute myeloid leukemia cell line but dispensable for normal hematopoiesis
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DOI: 10.1097/cm9.0000000000000878
Abstract: Supplemental Digital Content is available in the text read more here.
Keywords: containing protein; zinc finger; finger btb; protein essential ... See more keywords
Sibling rivalry among the ZBTB transcription factor family: homodimers versus heterodimers
Sign Up to like & getrecommendations! Published in 2022 at "Life Science Alliance"
DOI: 10.26508/lsa.202201474
Abstract: BTB domains potentially can form homo- or heterodimers. The study examines the dimerization choice of several BTB domains and finds only one heterodimer, while all tested pairs can homodimerize. The BTB domain is an oligomerization… read more here.
Keywords: zbtb transcription; btb domain; family;