Blast-related traumatic brain injury is mediated by the kynurenine pathway
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DOI: 10.1097/wnr.0000000000001817
Abstract: Objectives The overactivation of the kynurenine pathway, the major metabolic pathway of tryptophan, induced by inflammation and oxidative stress, might bring about excessive neurotoxic metabolites. This study aimed to investigate whether kynurenine pathway is overactivated… read more here.
Keywords: kynurenine pathway; blast related; inhibitor; btbi ... See more keywords
Chronic effects of blast injury on the microvasculature in a transgenic mouse model of Alzheimer’s disease related Aβ amyloidosis
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DOI: 10.1186/s12987-021-00301-z
Abstract: Background Altered cerebrovascular function and accumulation of amyloid-β (Aβ) after traumatic brain injury (TBI) can contribute to chronic neuropathology and increase the risk for Alzheimer’s disease (AD). TBI due to a blast-induced shock wave (bTBI)… read more here.
Keywords: btbi; group; injury; months survival ... See more keywords