Long term beneficial effect of neurotrophic factors-secreting mesenchymal stem cells transplantation in the BTBR mouse model of autism
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.03.047
Abstract: HighlightsMSC and NurOwn® treatments induced a long‐lasting effect of amelioration of autistic‐like behaviors.NurOwn® treatment had advantages over MSC treatment in terms of communication and stereotypic behavior.Both MSC and NurOwn® treatments induced a long‐lasting improvement in… read more here.
Keywords: improvement; btbr; treatment; effect ... See more keywords
Beneficial Effects of Fingolimod on Social Interaction, CNS and Peripheral Immune Response in the BTBR Mouse Model of Autism
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2020.03.041
Abstract: Autism Spectrum Disorders (ASD) are neurodevelopmental disorders characterized by social communication deficits and repetitive/stereotyped behaviours. We evaluated the effects of a chronic treatment with the immunomodulator drug Fingolimod (FTY720 - a non-selective Sphingosine 1-Phosphate Receptor… read more here.
Keywords: fty720; btbr; autism; model ... See more keywords
Circadian Responses to Light in the BTBR Mouse
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biological Rhythms"
DOI: 10.1177/07487304221102279
Abstract: Animals with altered freerunning periods are valuable in understanding properties of the circadian clock. Understanding the relationship between endogenous clock properties, entrainment, and influence of light in terms of parametric and non-parametric models can help… read more here.
Keywords: phase; circadian responses; btbr mice; btbr ... See more keywords
Kidney microRNA Expression Pattern in Type 2 Diabetic Nephropathy in BTBR Ob/Ob Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.778776
Abstract: Diabetic nephropathy (DN) is the main leading cause of chronic kidney disease worldwide. Although remarkable therapeutic advances have been made during the last few years, there still exists a high residual risk of disease progression… read more here.
Keywords: expression pattern; kidney; btbr mice; btbr ... See more keywords
Proteomic-Based Approach Reveals the Involvement of Apolipoprotein A-I in Related Phenotypes of Autism Spectrum Disorder in the BTBR Mouse Model
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315290
Abstract: Autism spectrum disorder (ASD) is a neurodevelopmental disorder. Abnormal lipid metabolism has been suggested to contribute to its pathogenesis. Further exploration of its underlying biochemical mechanisms is needed. In a search for reliable biomarkers for… read more here.
Keywords: spectrum disorder; autism spectrum; disorder; btbr ... See more keywords