The Stat3 inhibitor, S3I-201, downregulates lymphocyte activation markers, chemokine receptors, and inflammatory cytokines in the BTBR T+ Itpr3tf/J mouse model of autism
Sign Up to like & getrecommendations! Published in 2019 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2019.07.006
Abstract: Autism is a complex neurodevelopmental disorder with a high incidence rate. It is characterized by deficits in communication, a lack of social skills, cognitive inflexibility, and stereotypical behaviors. Autism has been gradually increasing in children… read more here.
Keywords: autism; stat3 inhibitor; btbr mice; btbr itpr3tf ... See more keywords
Effects of environmental enrichment and sexual dimorphism on the expression of cerebellar receptors in C57BL/6 and BTBR + Itpr3tf/J mice
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DOI: 10.21203/rs.3.rs-1140363/v1
Abstract: Objective Environmental enrichment is used to treat social, communication, and behavioral deficits and is known to modify the expression of synaptic receptors. We compared the effects of environmental enrichment in the expression of glutamate and… read more here.
Keywords: environmental enrichment; expression; effects environmental; itpr3tf mice ... See more keywords