The Bordetella effector protein BteA induces host cell death by disruption of calcium homeostasis
Sign Up to like & getrecommendations! Published in 2024 at "mBio"
DOI: 10.1128/mbio.01925-24
Abstract: ABSTRACT Bordetella pertussis is the causative agent of whooping cough in humans, a disease that has recently experienced a resurgence. In contrast, Bordetella bronchiseptica infects the respiratory tract of various mammalian species, causing a range… read more here.
Keywords: host; bordetella; btea; cell death ... See more keywords
BopN is a Gatekeeper of the Bordetella Type III Secretion System
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.04112-22
Abstract: The T3SS is utilized by many Gram-negative bacteria to deliver effector proteins from bacterial cytosol directly into infected host cell cytoplasm in a regulated and targeted manner. Pathogenic bordetellae use the T3SS to inject the… read more here.
Keywords: bordetella; btea; secretion; host ... See more keywords
Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1008512
Abstract: Bordetella bronchiseptica and Bordetella pertussis are closely related respiratory pathogens that evolved from a common bacterial ancestor. While B. bronchiseptica has an environmental reservoir and mostly establishes chronic infections in a broad range of mammals,… read more here.
Keywords: bordetella; insertion; btea; cytotoxicity ... See more keywords