Friend or Foe: Prognostic and Immunotherapy Roles of BTLA in Colorectal Cancer
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DOI: 10.3389/fmolb.2020.00148
Abstract: Background B and T lymphocyte attenuator (BTLA) is a co-signaling protein belonging to the CD28 immunoglobulin superfamily. However, the role of BTLA in prognosis and immunotherapy of colorectal cancer (CRC) remains unclear. Methods We evaluated… read more here.
Keywords: btla; immunotherapy; btla expression; colorectal cancer ... See more keywords
BTLA Expression on Th1, Th2 and Th17 Effector T-Cells of Patients with Systemic Lupus Erythematosus Is Associated with Active Disease
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DOI: 10.3390/ijms20184505
Abstract: An imbalanced T-cell homeostasis plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). Co-stimulatory and co-inhibitory molecules regulate T-cell differentiation, survival, and cytokine production. B- and T-lymphocyte attenuator (BTLA) is a co-inhibitory… read more here.
Keywords: btla; btla expression; systemic lupus; disease ... See more keywords
B- and T-Lymphocyte Attenuator Expression on Regulatory T-Cells in Patients with Severe Sepsis
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DOI: 10.4103/0366-6999.244104
Abstract: To the Editor: Regulatory T‐cells (Tregs), a subset of CD4+ T‐cells, have the capacity to actively suppress immune responses and play a pivotal role in sepsis‐induced immunosuppression.[1] B‐ and T‐lymphocyte attenuator (BTLA) is a co‐inhibitory… read more here.
Keywords: sepsis; btla expression; regulatory cells; expression ... See more keywords