E3 ubiquitin ligase BTRC inhibits the proliferation and tumor growth of glioma cells through the NFAT5/AQP4 axis
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-025-06346-z
Abstract: Ubiquitination is integral to the pathogenesis of various tumors. This study sought to elucidate the role and underlying mechanisms of BTRC-mediated ubiquitination and degradation in glioma. The expression levels of beta-transduced in repeat containing E3… read more here.
Keywords: nfat5 aqp4; tumor growth; glioma cells; btrc ... See more keywords
Microduplication of BTRC detected in a Chinese family with split hand/foot malformation type 3
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DOI: 10.1111/cge.14204
Abstract: Split hand/foot malformation (SHFM) is a clinically heterogeneous genetic disorder, which is mainly characterized by median clefts of the hand/feet due to the absence of the central digital rays. Several subgroups of SHFM have been… read more here.
Keywords: family; microduplication; malformation; hand ... See more keywords
Knockdown of Gfi1 increases BMSCs exosomal miR-150-3p to inhibit osteoblast ferroptosis in steroid-induced osteonecrosis of the femoral head through BTRC/Nrf2 axis
Sign Up to like & getrecommendations! Published in 2024 at "Endocrine Journal"
DOI: 10.1507/endocrj.ej24-0306
Abstract: The ferroptosis of osteoblasts has been demonstrated to play a significant role in the development of steroid-induced osteonecrosis of the femoral head (SONFH). Additionally, microRNAs (miRNAs) have been identified as regulators of SONFH progression. However,… read more here.
Keywords: osteoblast ferroptosis; mir 150; ferroptosis; gfi1 ... See more keywords