Loss of Centromere Cohesion in Aneuploid Human Oocytes Correlates with Decreased Kinetochore Localization of the Sac Proteins Bub1 and Bubr1
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DOI: 10.1038/srep44001
Abstract: In human eggs, aneuploidy increases with age and can result in infertility and genetic diseases. Studies in mouse oocytes suggest that reduced centromere cohesion and spindle assembly checkpoint (SAC) activity could be at the origin… read more here.
Keywords: bub1 bubr1; centromere cohesion; human oocytes; sac ... See more keywords