Evidence of Systemic Absorption of Enteral Budesonide in Patients with Fontan-Associated Protein-Losing Enteropathy
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DOI: 10.1007/s00246-019-02248-3
Abstract: To evaluate for evidence of systemic glucocorticoid absorption in cases of Fontan-associated protein-losing enteropathy (PLE) treated with enteral budesonide, we reviewed the charts of 27 patients with Fontan-associated PLE followed at Children’s Hospital Colorado from… read more here.
Keywords: absorption; associated protein; fontan associated; evidence systemic ... See more keywords
Continuous flow process for preparing budesonide
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DOI: 10.1007/s41981-022-00221-5
Abstract: Budesonide, a glucocorticosteroid, is used as anti-asthmatic drug that became generic in 2019. Existing preparation methods of budesonide require utilization of corrosive acids and involve expensive purification process. Thus, a new cost-effective continuous flow process… read more here.
Keywords: process; continuous flow; budesonide; flow process ... See more keywords
A placebo-controlled randomised trial of budesonide for primary biliary cholangitis following an insufficient response to UDCA.
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DOI: 10.1016/j.jhep.2020.09.011
Abstract: BACKGROUND & AIMS In patients with primary biliary cholangitis (PBC) the utility of budesonide, a synthetic corticosteroid displaying high first-pass metabolism, is unresolved. In a placebo-controlled, double-blind trial, we evaluated the added-value of budesonide in… read more here.
Keywords: primary biliary; budesonide; placebo controlled; biliary cholangitis ... See more keywords
[Off-label use of Budesonide suspensions to treat a patient with lymphocytic esophagitis].
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DOI: 10.1055/s-0043-117187
Abstract: Background Lymphocytic esophagitis (LyE) is a rare chronic inflammatory disease of the esophagus, which shares clinical characteristics with the eosinophilic esophagitis. The most important part of its treatment is proton pump inhibitors (PPIs). Referring to locally… read more here.
Keywords: esophagitis; treatment; label use; lymphocytic esophagitis ... See more keywords
A meta-analysis on randomized controlled trials of treating eosinophilic esophagitis with budesonide
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DOI: 10.1080/07853890.2022.2101689
Abstract: Abstract Objective Eosinophilic esophagitis (EoE) is a chronic, local immune-mediated inflammatory oesophageal disease. Although Budesonide is recommended as one of the first-line drugs for EoE treatment, its efficacy is still controversial in multiple studies. Due… read more here.
Keywords: meta analysis; budesonide; eosinophilic esophagitis; controlled trials ... See more keywords
Biophysical and chemical stability of surfactant/budesonide and the pulmonary distribution following intra-tracheal administration
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DOI: 10.1080/10717544.2019.1618418
Abstract: Abstract Intra-tracheal instillation of budesonide using surfactant as a vehicle significantly decreased the incidence of bronchopulmonary dysplasia or death in preterm infants. The formularity of surfactant supplemented with budesonide and biophysical and chemical stability of… read more here.
Keywords: chemical stability; intra tracheal; biophysical chemical; curosurf ... See more keywords
Oral liposomal delivery of an activatable budesonide prodrug reduces colitis in experimental mice
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DOI: 10.1080/10717544.2023.2183821
Abstract: Abstract Inflammatory bowel disease (IBD) is one of the most common intestinal disorders, with increasing global incidence and prevalence. Numerous therapeutic drugs are available but require intravenous administration and are associated with high toxicity and… read more here.
Keywords: liposomal delivery; budesonide; oral liposomal; delivery activatable ... See more keywords
Immune-checkpoint inhibitor-associated grade 3 hepatotoxicity managed with enteric-coated budesonide monotherapy: A case report
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DOI: 10.1097/md.0000000000029473
Abstract: Rationale: The introduction of immune-checkpoint inhibitors (ICPI) in recent years has changed the natural course of many neoplasms. However, patients receiving these medications may present immune-mediated adverse events; management includes temporary or permanent cessation of… read more here.
Keywords: budesonide; immune checkpoint; enteric coated; budesonide monotherapy ... See more keywords
Early Physiological and Adrenal Effects of Budesonide Mixed with Surfactant in Large Observational Preterm Cohort Study
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DOI: 10.1159/000524614
Abstract: Background: The combination of surfactant and budesonide has been shown to decrease BPD rates and severity. Budesonide may be released systemically from lungs, and the effects on the immature adrenal glands are not known. Objective:… read more here.
Keywords: adrenal effects; budesonide; receiving budesonide; early physiological ... See more keywords