Possible genetical predictors of efficacy and safety of budesonide-MMX in patients with mild-to-moderate ulcerative colitis, and safety comparison with methylprednisolone.
Sign Up to like & getrecommendations! Published in 2023 at "Expert opinion on drug safety"
DOI: 10.1080/14740338.2023.2181336
Abstract: BACKGROUND Budesonide-MMX is a topically active corticosteroid degraded by cytochrome-P450 enzymes, resulting in favourable side-effect profile. We aimed to assess effect of CYP genotypes on safety and efficacy, and make a direct comparison with systemic… read more here.
Keywords: safety; budesonide mmx; methylprednisolone; comparison ... See more keywords
Comparative assessment of budesonide-MMX and mesalamine in active, mild-to-moderate ulcerative colitis: a systematic review and network meta-analysis.
Sign Up to like & getrecommendations! Published in 2019 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.14051
Abstract: AIM The comparative efficacy, safety and tolerability of budesonide-MMX and oral mesalamine in active, mild-to-moderate ulcerative colitis (UC) are unclear. We conducted a network meta-analysis to fill this evidence gap. METHODS We searched PubMed, Scopus,… read more here.
Keywords: mesalamine; budesonide mmx; mesalamine day; active mild ... See more keywords