Bufalin induces apoptosis and autophagy via the Ca2+/CaMKKβ/AMPK/Beclin1 signaling pathway in osteosarcoma cells.
Sign Up to like & getrecommendations! Published in 2023 at "Cell biology international"
DOI: 10.1002/cbin.12021
Abstract: Bufalin, a major cardiotonic compound of the traditional Chinese medicine Chanshu has been used for cancer treatment for several years. However, the molecular mechanisms of Bufalin-induced autophagy in osteosarcoma (OS) is not fully understood. In… read more here.
Keywords: ampk beclin1; apoptosis autophagy; bufalin; bufalin induced ... See more keywords
Bufalin induced apoptosis of bladder carcinoma cells through the inactivation of Na+K+-ATPase
Sign Up to like & getrecommendations! Published in 2018 at "Oncology Letters"
DOI: 10.3892/ol.2018.9142
Abstract: Bufalin has been demonstrated to possess a wide range of pharmacological effects. Among these is its antitumour effect, which has been confirmed in multiple organs or tissues and provoked many concerns. However, its cytostatic effect… read more here.
Keywords: bufalin; apoptosis; bladder; inactivation ... See more keywords