Overcoming the Challenges of Low Drug Solubility in the Intravenous Formulation of Solithromycin.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.10.030
Abstract: Solithromycin is a fluoro-ketolide (a fourth-generation macrolide) antibiotic that has been undergoing clinical trials for the treatment of community-acquired bacterial pneumonia. In this study, development of the tri-amino acid-buffered solithromycin intravenous (IV) formulation was performed… read more here.
Keywords: buffered formulation; solithromycin; formulation; overcoming challenges ... See more keywords