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Published in 2021 at "Drug discovery today"
DOI: 10.1016/j.drudis.2021.08.009
Abstract: Biological drugs or biopharmaceuticals off patent open a large market for biosimilars and biobetters, follow-on biologics. Biobetters, in particular, are new drugs designed from existing ones with improved properties such as higher selectivity, stability, half-life…
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Keywords:
building better;
industrial application;
fundamentals industrial;
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Published in 2021 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2021.166894
Abstract: β-barrel proteins are folded and inserted into outer membranes by multi-subunit protein complexes that are conserved across different types of outer membranes. In Gram-negative bacteria this complex is the barrel-assembly machinery (BAM), in mitochondria it…
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building better;
barrel;
better barrels;
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Published in 2021 at "Eos"
DOI: 10.1029/2021eo155818
Abstract: Researchers collaborated to produce and evaluate a new version of the Community Earth System Model, and they are documenting their work in the AGU CESM2 virtual special issue.
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Keywords:
view earth;
building better;
better model;
model ... See more keywords
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Published in 2020 at "Nature"
DOI: 10.1038/d41586-020-02675-w
Abstract: The current technique requires a person’s own cells, but using the cells of healthy donors could allow more people to benefit. The current technique requires a person’s own cells, but using the cells of healthy…
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Keywords:
building better;
better car;
car therapies;
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Published in 2019 at "Nature Energy"
DOI: 10.1038/s41560-019-0483-2
Abstract: The world is becoming more complex for policymakers and researchers alike as climate change, new technology and digitalization drive unprecedented energy-system change. Understanding one another is paramount if we are to address the challenges they…
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building better;
dialogue energy;
energy research;
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Published in 2017 at "Scientific American"
DOI: 10.1038/scientificamerican0517-26
Abstract: The article focuses on the origin and use of batteries. It includes information the development of hugh capacity batteries on cheaper prices. It also includes information on the replacement of highly flammable liquid electrolyte batteries…
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better battery;
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Published in 2017 at "Scientific American"
DOI: 10.1038/scientificamerican0817-66
Abstract: The article offers information on efforts of agricultural scientists to develop methods of protecting crops from threats and pests and increase yields. It mentions the impact of microbes in plant defense mechanism along with their…
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better harvest;
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Published in 2019 at "Technical Communication Quarterly"
DOI: 10.1080/10572252.2019.1583378
Abstract: ABSTRACT In this article the authors envision a more durable and portable model of scholarship on public engagement with science through partnerships between rhetoricians of science and quantitative social scientists. The authors consider a number…
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communication;
science;
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Published in 2017 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2017.1251839
Abstract: Familial chylomicronemia syndrome (FCS), also referred to as type 1 hyperlipoproteinemia or lipoprotein lipase deficiency, is a rare genetic lipid disorder characterized by severe elevations in cir...
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Keywords:
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familial chylomicronemia;
better understanding;
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Published in 2018 at "Annals of Oncology"
DOI: 10.1093/annonc/mdx790
Abstract: Despite the unheralded success of immune checkpoint blockade in delivering durable responses for some patients with non-small-cell lung cancer (NSCLC), the majority of patients do not respond. PD-L1 tumour expression and pre-existing tumour T-cell infiltration…
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building better;
research platforms;
better translational;
lung cancer ... See more keywords
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Published in 2018 at "Environmental History"
DOI: 10.1093/envhis/emy046
Abstract: The emergent or newly reemerging disease model often relies on poverty as a contributing factor in the transmission of infectious diseases. But as Andrew Price-Smith has argued, affluence can also be a factor in the…
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Keywords:
legionnaires disease;
building better;
disease building;
disease ... See more keywords