A mutational hotspot that determines highly repeatable evolution can be built and broken by silent genetic changes.
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DOI: 10.1038/s41467-021-26286-9
Abstract: Mutational hotspots can determine evolutionary outcomes and make evolution repeatable. Hotspots are products of multiple evolutionary forces including mutation rate heterogeneity, but this variable is often hard to identify. In this work, we reveal that… read more here.
Keywords: built broken; evolution; mutational hotspot; highly repeatable ... See more keywords