Evolution of bulbar function in spinal muscular atrophy type 1 treated with nusinersen.
Sign Up to like & getrecommendations! Published in 2022 at "Developmental medicine and child neurology"
DOI: 10.1111/dmcn.15171
Abstract: AIM To assess the evolution of bulbar function in nusinersen-treated spinal muscular atrophy type 1 (SMA1). METHOD This single-centre retrospective study identified 24 patients (14 females and 10 males) with SMA1, treated with nusinersen between… read more here.
Keywords: muscular atrophy; bulbar function; bulbar; evolution bulbar ... See more keywords
Assessment of bulbar function in amyotrophic lateral sclerosis: validation of a self‐report scale (Center for Neurologic Study Bulbar Function Scale)
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Neurology"
DOI: 10.1111/ene.13638
Abstract: Impaired bulbar functions of speech and swallowing are among the most serious consequences of amyotrophic lateral sclerosis (ALS). Despite this, clinical trials in ALS have rarely emphasized bulbar function as an endpoint. The rater‐administered Amyotrophic… read more here.
Keywords: bulbar; bulbar function; amyotrophic lateral; lateral sclerosis ... See more keywords
Patients with Spinal Muscular Atrophy Type 1 Achieve and Maintain Bulbar Function Following Onasemnogene Abeparvovec Treatment.
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DOI: 10.3233/jnd-221531
Abstract: BACKGROUND Improvement and maintenance of bulbar function are goals of disease-modifying treatments for spinal muscular atrophy (SMA). Lack of standardized measures and a widely accepted definition of bulbar function represents a gap in SMA care.… read more here.
Keywords: spinal muscular; bulbar; onasemnogene abeparvovec; muscular atrophy ... See more keywords
Assessing Bulbar Function in Spinal Muscular Atrophy Using Patient-Reported Outcomes.
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DOI: 10.3233/jnd-221573
Abstract: BACKGROUND Novel Spinal Muscular Atrophy (SMA) treatments have demonstrated improvements on motor measures that are clearly distinct from the natural history of progressive decline. Comparable measures are needed to monitor bulbar function, which is affected… read more here.
Keywords: spinal muscular; bulbar; patient reported; muscular atrophy ... See more keywords
An Automated Tongue Tracker for Quantifying Bulbar Function in ALS
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DOI: 10.3389/fneur.2022.838191
Abstract: Introduction Bulbar symptoms, including difficulty swallowing and speaking, are common in amyotrophic lateral sclerosis (ALS) and other neurological disorders, such as stroke. The presence of bulbar symptoms provides important information regarding clinical outcomes, such as… read more here.
Keywords: bulbar; tongue; limb onset; tongue tracker ... See more keywords