Articles with "bulevirtide" as a keyword



Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP

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Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-46706-w

Abstract: Cellular entry of the hepatitis B and D viruses (HBV/HDV) requires binding of the viral surface polypeptide preS1 to the hepatobiliary transporter Na+-taurocholate co-transporting polypeptide (NTCP). This interaction can be blocked by bulevirtide (BLV, formerly… read more here.

Keywords: hbv hdv; bulevirtide; structure; hepatitis ... See more keywords