Improving Catalytic Activity and Reversing Enantio‐Specificity of ω‐Transaminase by Semi‐Rational Engineering en Route to Chiral Bulky β‐Amino Esters
Sign Up to like & getrecommendations! Published in 2021 at "ChemCatChem"
DOI: 10.1002/cctc.202100503
Abstract: The application of wild‐type ω‐transaminase was limited by steric hindrance towards bulky substrates, therefore improvement of the catalytic efficiency and stereoselectivity toward substrates with two bulky substituent adjacent to the carbonyl is of general interest.… read more here.
Keywords: bulky; keto esters; reversing enantio; transaminase ... See more keywords
Approaches to The Hagfeldt Donor and Use of Next Generation Bulky Donor Designs in Dye-Sensitized Solar Cell Dyes.
Sign Up to like & getrecommendations! Published in 2020 at "ChemSusChem"
DOI: 10.1002/cssc.202000409
Abstract: 'The Hagfeldt donor' is a bulky triarylamine building block with 4 alkyl chains in a 3-dimensional arrangement which is used with organic dyes in dye-sensitized solar cells (DSCs) in over 140 manuscripts. Many of the… read more here.
Keywords: bulky; hagfeldt donor; dye sensitized; sensitized solar ... See more keywords
Effect of pendent bulky groups on pure- and sour mixed-gas permeation properties of triphenylamine-based polyimides
Sign Up to like & getrecommendations! Published in 2019 at "Separation and Purification Technology"
DOI: 10.1016/j.seppur.2019.115713
Abstract: Abstract Three diamine triphenylamine-based monomers, 4,4′-diaminotriphenylamine (TPA), 4,4′-diamino-4″-(dimethylamino)triphenylamine (TPA(NMe2)), and 4,4′-diamino-4″-(tert-butyl)triphenylamine (TPA(t-Bu)) were reproduced in preparation for their 6FDA-based homopolyimides: 6FDA-TPA, 6FDA-TPA(NMe2) and 6FDA-TPA(t-Bu). The bulkiness effect of two pendent groups (dimethylamino and tert-butyl) on… read more here.
Keywords: gas; 6fda tpa; mixed gas; bulky ... See more keywords
Synthesis of the Bulky Phosphanide [P(SiiPr3)2]− and Its Stabilization of Low-Coordinate Group 12 Complexes
Sign Up to like & getrecommendations! Published in 2024 at "Inorganic Chemistry"
DOI: 10.1021/acs.inorgchem.4c03134
Abstract: Here, we report an improved synthesis of the bulky phosphanide anion [P(SiiPr3)2]− in synthetically useful yields and its complexation to group 12 metals. The ligand is obtained as the sodium salt NaP(SiiPr3)21 in a 42%… read more here.
Keywords: bulky; group; synthesis; synthesis bulky ... See more keywords
Coatable 2D Conjugated Polymers Containing Bulky Macromolecular Guests for Thermal Imaging.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c12909
Abstract: Dynamic properties are derived from the structural flexibility of 2D polymers. Softening layered structures has the potential for tuning and enhancing the dynamic properties. In the present work, the flexibility of layered polydiacetylene (PDA) is… read more here.
Keywords: dynamic properties; thermoresponsive color; thermal imaging; bulky ... See more keywords
Cu(i) complex bearing a PNP-pincer-type phosphaalkene ligand with a bulky fused-ring Eind group: properties and applications to FLP-type bond activation and catalytic CO2 reduction.
Sign Up to like & getrecommendations! Published in 2020 at "Dalton transactions"
DOI: 10.1039/d0dt00276c
Abstract: Herein, we report the synthesis of [Cu(Eind2-BPEP)][PF6] (2) (Eind2-BPEP = 2,6-bis(2-Eind-2-phosphaethenyl)pyridine, Eind = 1,1,3,3,5,5,7,7-octaethyl-1,2,3,5,6,7-hexahydro-s-indacen-4-yl), a three-coordinated Cu(i) complex bearing a PNP-pincer-type phosphaalkene ligand with bulky fused-ring Eind groups. The Gutmann-Beckett test revealed that complex 2… read more here.
Keywords: complex bearing; bulky; pnp pincer; pincer type ... See more keywords
A series of (E)-1,2-diaryldigermenes incorporating bulky Eind groups: structural characteristics and absorption properties.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.1039/d2dt03427a
Abstract: A series of (E)-1,2-diaryldigermenes, (Eind)ArGeGeAr(Eind) [Ar = phenyl (2), thiophen-2-yl (3), 9,9-dimethyl-2-fluorenyl (4) and 2,2'-bithiophen-5-yl (5)], supported by the fused-ring bulky 1,1,3,3,5,5,7,7-octaethyl-s-hydrindacen-4-yl (Eind) groups, have been obtained as yellow-orange to red crystalline solids by the… read more here.
Keywords: series diaryldigermenes; eind groups; absorption; bulky ... See more keywords
Discovery of Two Native Baeyer-Villiger Monooxygenases for Asymmetric Synthesis of Bulky Chiral Sulfoxides
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DOI: 10.1128/aem.00638-18
Abstract: ABSTRACT Two Baeyer-Villiger monooxygenases (BVMOs), designated BoBVMO and AmBVMO, were discovered from Bradyrhizobium oligotrophicum and Aeromicrobium marinum, respectively. Both monooxygenases displayed novel features for catalyzing the asymmetric sulfoxidation of bulky and pharmaceutically relevant thioethers. Evolutionary… read more here.
Keywords: baeyer; chiral sulfoxides; bulky; baeyer villiger ... See more keywords
Importance of bulky lymph node involvement in locally advanced anal cancer.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.16_suppl.e15500
Abstract: e15500 Background: Anal squamous carcinoma accounts for 0.1% of global cancer cases, with rising incidence and mortality trends in the last decade. We want to demonstrate in this study that bulky lymph node involvement is… read more here.
Keywords: bulky; rpfs; node involvement; bulky lymph ... See more keywords
Induction PD-1 inhibitor toripalimab plus chemotherapy followed by concurrent chemoradiotherapy and consolidation toripalimab for bulky locally advanced non-small-cell lung cancer: protocol for a randomized phase II trial (InTRist study)
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1341584
Abstract: Background Immune checkpoint inhibitors (ICIs) have revolutionized the treatment landscape for locally advanced non-small-cell lung cancer (LA-NSCLC), whereas responses to anti-programmed cell death-1 (PD-1) or anti-programmed death-ligand 1 (PD-L1) are heterogeneous. Though consolidation ICI following… read more here.
Keywords: bulky; plus chemotherapy; toripalimab plus; consolidation ... See more keywords
A Novel Radiotherapeutic Approach to Treat Bulky Metastases Even From Cutaneous Squamous Cell Carcinoma: Its Rationale and a Look at the Reliability of the Linear-Quadratic Model to Explain Its Radiobiological Effects
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.809279
Abstract: Introduction Metastatic cutaneous squamous cell carcinoma (cSCC) is a very rare condition. The lack of definition of an oligometastatic subgroup means that there is no consensus for its treatment, unlike the mucosal head and neck… read more here.
Keywords: treat bulky; cell carcinoma; bulky; cutaneous squamous ... See more keywords