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Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.0c02944
Abstract: As a nonaddictive analgesic widely used in clinics, the LD50 of bulleyaconitine A is just only 0.92 mg/kg, which exhibits obvious toxicity. Therefore, 31 new non-natural C19-diterpenoid alkaloids (2a–w, 2′a–e, 3, 4a, and 4b) were…
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Keywords:
derivatives analgesics;
new bulleyaconitine;
bulleyaconitine derivatives;
evaluation series ... See more keywords