Clarifications regarding bumetanide for neonatal seizures
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DOI: 10.1111/epi.17278
Abstract: A recent Phase II randomized, controlled trial of bumetanide as an adjunctive treatment for neonatal seizures showed a robust efficacy signal and no evidence of toxicity. Concerns regarding bumetanide as an adjunctive anticonvulsant are addressed… read more here.
Keywords: bumetanide neonatal; clarifications regarding; neonatal seizures; regarding bumetanide ... See more keywords
Bumetanide for neonatal seizures: No light in the pharmacokinetic/dynamic tunnel
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DOI: 10.1111/epi.17279
Abstract: In his editorial, Kevin Staley criticizes our recent work demonstrating the lack of effect of bumetanide in a novel model of neonatal seizures. The main points in our response are that (1) our work is… read more here.
Keywords: brain; light pharmacokinetic; bumetanide neonatal; neonatal seizures ... See more keywords