Bupleurum chinense DC improves CUMS-induced depressive symptoms in rats through upregulation of the cAMP/PKA/CREB signalling pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2022.115034
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Bupleurum chinense DC. (B. chinense) is the dried root of B. chinense, belonging to the Umbelliferae family. B. chinense has been reported since ancient times for its effect of soothing the liver and… read more here.
Keywords: camp; chinense; bupleurum chinense; depression ... See more keywords
Polysaccharides extracted from the roots of Bupleurum chinense DC modulates macrophage functions.
Sign Up to like & getrecommendations! Published in 2017 at "Chinese journal of natural medicines"
DOI: 10.1016/s1875-5364(18)30004-9
Abstract: The present study aimed to investigate the effects of polysaccharides extracted from Bupleurum chinense DC (BCPs) on macrophage functions. In the in vivo experiment, 1 mL of 5% sodium thioglycollate was injected into the abdomen… read more here.
Keywords: polysaccharides extracted; roots bupleurum; extracted roots; macrophage functions ... See more keywords
Aromatic glycosides from the aerial part of Bupleurum chinense.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Asian natural products research"
DOI: 10.1080/10286020.2021.2017897
Abstract: A new aromatic glycoside (1) and twelve (2-13) known aromatic glycosides were isolated from the n-butyl alcohol of the 70% EtOH extract of the aerial part of Bupleurum chinense. Among them, compounds 4-7, 9, 11-13… read more here.
Keywords: bupleurum chinense; part bupleurum; aromatic glycosides; aerial part ... See more keywords
Prokinetic effects of Citrus reticulata and Citrus aurantium extract with/without Bupleurum chinense using multistress-induced delayed gastric emptying models
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2023.2173249
Abstract: Abstract Context Citrus aurantium L (Rutaceae) (Au) and Citrus reticulata Blanco (Rutaceae) (Ci) are commonly used as couplet prokinetics and Bupleurum chinense DC. (Umbelliferae) (Bup) is an herbal antidepressant in traditional Chinese medicine. Objective This… read more here.
Keywords: citrus reticulata; bupleurum chinense; prokinetic effects; citrus aurantium ... See more keywords
Identification and potential mechanism of different components from the aerial part of Bupleurum chinense DC. for epileptic treatment
Sign Up to like & getrecommendations! Published in 2022 at "Natural Product Research"
DOI: 10.1080/14786419.2022.2055557
Abstract: Abstract The present study aimed to assess the effects of epileptic treatment of the aerial part of Bupleurum chinense DC. in kainic acid (KA)-induced epilepsy rats and LPS-induced BV2 cells, as well as to identify… read more here.
Keywords: bupleurum chinense; aerial part; epileptic treatment; part bupleurum ... See more keywords
Extraction, characterization, antioxidation and anti-inflammatory activity of polysaccharides from Bupleurum chinense based on different molecular weights
Sign Up to like & getrecommendations! Published in 2024 at "Natural Product Research"
DOI: 10.1080/14786419.2024.2357667
Abstract: Abstract Bupleurum chinense polysaccharide has a wide range of biological activities. In this study, Bupleurum chinense polysaccharides (BPs), BPs-1 (30 kDa) and BPs-2 (2000 kDa) with different molecular weights were isolated and prepared by ultrafiltration interception method.… read more here.
Keywords: bps bps; bupleurum chinense; activity; chinense ... See more keywords
Revealing the anti-inflammatory mechanisms of Bupleurum chinense DC. through network pharmacology and experimental validation.
Sign Up to like & getrecommendations! Published in 2025 at "Natural product research"
DOI: 10.1080/14786419.2025.2587320
Abstract: A comprehensive approach combining network pharmacology, molecular docking and in vitro validation was used to systematically elucidate anti-inflammatory mechanisms of bioactive -compounds from the Bupleurum chinense DC aerial parts. Compound-Target network and PPI network were… read more here.
Keywords: network pharmacology; pharmacology; bupleurum chinense; network ... See more keywords
Chromosome-Level Genome Assembly of Bupleurum chinense DC Provides Insights Into the Saikosaponin Biosynthesis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.878431
Abstract: Bupleurum chinense DC is a plant widely used in Chinese traditional medicine. Saikosaponins are the major bioactive constituents of B. chinense DC. Saikosaponins biosynthesis in Bupleurum has been more intensively studied than any other metabolic… read more here.
Keywords: biosynthesis; bupleurum chinense; genome; chromosome level ... See more keywords
Metabolomics Analysis Reveals the Differences Between Bupleurum chinense DC. and Bupleurum scorzonerifolium Willd.
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.933849
Abstract: Bupleurum chinense DC. and Bupleurum scorzonerifolium Willd. are two varieties of Bupleuri Radix in Chinese Pharmacopoeia 2020. The clinical efficacy of the two bupleurum species is different. The difference in clinical efficacy is closely related… read more here.
Keywords: bupleurum chinense; scorzonerifolium willd; bupleurum scorzonerifolium; analysis ... See more keywords
Drought Stress Stimulates the Terpenoid Backbone and Triterpenoid Biosynthesis Pathway to Promote the Synthesis of Saikosaponin in Bupleurum chinense DC. Roots
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27175470
Abstract: Bupleurum chinense is an important medicinal plant in China; however, little is known regarding how this plant transcribes and synthesizes saikosaponins under drought stress. Herein, we investigated how drought stress stimulates the transcriptional changes of… read more here.
Keywords: stress; bupleurum chinense; stage; drought stress ... See more keywords