Buprenorphine, Pain, and Opioid Use in Patients Taking High-Dose Long-Term Opioids: A Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2025 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2024.8361
Abstract: Importance Guidelines recommend dose reduction or discontinuation of long-term opioid therapy when harm outweighs benefit, but strategies to help patients do so are limited. Objective To test optionally switching to buprenorphine as a strategy for… read more here.
Keywords: buprenorphine; long term; pain; trial ... See more keywords
Patient-Reported Outcomes of Treatment of Opioid Dependence With Weekly and Monthly Subcutaneous Depot vs Daily Sublingual Buprenorphine: A Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2021.9041
Abstract: Importance Patient-reported outcomes in the treatment of opioid dependence may differ between subcutaneously administered depot buprenorphine and daily sublingual buprenorphine. Objective To compare patient satisfaction between depot buprenorphine and sublingual buprenorphine in adult outpatients with… read more here.
Keywords: trial; treatment; sublingual buprenorphine; buprenorphine ... See more keywords
Comparative Effectiveness Associated With Buprenorphine and Naltrexone in Opioid Use Disorder and Cooccurring Polysubstance Use
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.11363
Abstract: Key Points Question What is the prevalence and comparative effectiveness associated with buprenorphine and naltrexone in individuals with opioid use disorder (OUD) and cooccurring substance use disorders (SUDs)? Findings This comparative effectiveness study evaluated 179 280… read more here.
Keywords: buprenorphine; effectiveness associated; use; comparative effectiveness ... See more keywords
Buprenorphine Utilization and Prescribing Among New Jersey Medicaid Beneficiaries After Adoption of Initiatives Designed to Improve Treatment Access
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.12030
Abstract: Key Points Question Were initiatives aimed at improving access to buprenorphine treatment in New Jersey Medicaid associated with increases in buprenorphine utilization and prescribing? Findings This cross-sectional study of 20 090 Medicaid beneficiaries found that the… read more here.
Keywords: new jersey; medicaid; buprenorphine; jersey medicaid ... See more keywords
Impact of the Communities That HEAL Intervention on Buprenorphine-Waivered Practitioners and Buprenorphine Prescribing
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2024.0132
Abstract: Key Points Question Did the Communities That HEAL intervention increase the rate of practitioners with a Drug Addiction Treatment Act of 2000 waiver and prescribing of buprenorphine? Findings In this secondary analysis of a randomized… read more here.
Keywords: buprenorphine; rate; rate practitioners; heal intervention ... See more keywords
Initiating Injectable Buprenorphine in People Hospitalized With Infections
Sign Up to like & getrecommendations! Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2025.13000
Abstract: This randomized clinical trial of patients with opioid use disorder (OUD) hospitalized for infection examines whether initiating long-acting buprenorphine plus infectious disease management vs treatment as usual improves receipt of medications for OUD at 12… read more here.
Keywords: hospitalized infections; buprenorphine; initiating injectable; people hospitalized ... See more keywords
Association Between Buprenorphine Treatment Gaps, Opioid Overdose, and Health Care Spending in US Medicare Beneficiaries With Opioid Use Disorder.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2022.3118
Abstract: Importance Nonadherence to buprenorphine may increase patient risk of opioid overdose and increase health care spending. Quantifying the impacts of nonadherence can help inform clinician practice and policy. Objective To estimate the association between buprenorphine… read more here.
Keywords: buprenorphine treatment; opioid overdose; buprenorphine; treatment ... See more keywords
Association of Patients' Direct Addition of Buprenorphine to Urine Drug Test Specimens With Clinical Factors in Opioid Use Disorder.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2023.0234
Abstract: Importance The direct addition of buprenorphine to urine drug test specimens to mimic results suggestive of adherence is a clinically significant result, yet little is known about the phenomenon. Objective To characterize factors associated with… read more here.
Keywords: buprenorphine urine; direct addition; urine drug; buprenorphine ... See more keywords
Buprenorphine Continuation During Critical Illness Associated With Decreased Inpatient Opioid Utilization In Individuals Maintained On Buprenorphine For Opioid Use Disorder In A Retrospective Study.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of clinical pharmacology"
DOI: 10.1002/jcph.2286
Abstract: The number of patients maintained on buprenorphine is steadily increasing. To date, no study has reported buprenorphine management practices for these patients during critical illness, nor its relationship with supplemental full-agonist opioid administration during their… read more here.
Keywords: buprenorphine; opioid; use; study ... See more keywords
Frontline Science: Buprenorphine decreases CCL2‐mediated migration of CD14+CD16+ monocytes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3hi0118-015r
Abstract: HIV infection of the CNS causes neuroinflammation and damage that contributes to the development of HIV‐associated neurocognitive disorders (HAND) in greater than 50% of HIV‐infected individuals, despite antiretroviral therapy (ART). Opioid abuse is a major… read more here.
Keywords: hiv; cd16 monocytes; cd14 cd16; ccl2 mediated ... See more keywords
Dispersive solid-phase extraction of buprenorphine from biological fluids using metal-organic frameworks and its determination by ultra-performance liquid chromatography.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of separation science"
DOI: 10.1002/jssc.202000221
Abstract: In this work, various types of metal-organic frameworks were synthesized, and their affinities towards buprenorphine were evaluated using dispersive solid-phase extraction. The extracted buprenorphine was determined by ultra-performance liquid chromatography-ultraviolet detection system. The highest extraction… read more here.
Keywords: extraction; metal organic; solid phase; buprenorphine ... See more keywords