LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "bupropion" as a keyword



Real-world efficacy and safety of naltrexone-bupropion therapy in Chinese patients with obesity: A single-centre experience

Sign Up to like & get
recommendations! Published in 2024 at "Endocrine"

DOI: 10.1007/s12020-024-04029-2

Abstract: Naltrexone-bupropion (Contrave®) has shown efficacy and safety in large randomised controlled trials, predominantly comprising Caucasians. Data are limited in Asian populations. We carried out a retrospective matched cohort study of Chinese patients with obesity to… read more here.

Keywords: patients obesity; chinese patients; naltrexone bupropion; bupropion ... See more keywords

Blockade of nicotinic acetylcholine receptor enhances the responsiveness to bupropion in the mouse forced swim test

Sign Up to like & get
recommendations! Published in 2019 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2018.12.027

Abstract: HIGHLIGHTSRole of nicotinic receptors was tested in the antidepressant effects of bupropion.&agr;4, &agr;5, &agr;6, and &bgr;2 nicotinic receptor subunit WT&KO mice were studied using the FST.&agr;4, &agr;6, and &bgr;2 subunits modulate the antidepressant‐like effects of… read more here.

Keywords: agr bgr; agr; mice; agr agr ... See more keywords
Photo from wikipedia

Assessment of individual differences in response to acute bupropion or varenicline treatment using a long-access nicotine self-administration model and behavioral economics in female rats

Sign Up to like & get
recommendations! Published in 2020 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2020.112558

Abstract: Bupropion and varenicline are widely prescribed pharmacological treatments for smoking cessation. These treatments are only marginally effective in clinical populations but most preclinical studies show that they are effective in decreasing self-administration in rats on… read more here.

Keywords: nicotine; bupropion varenicline; bupropion; access ... See more keywords

In vitro to in vivo extrapolation of the complex drug‐drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation

Sign Up to like & get
recommendations! Published in 2017 at "Biochemical Pharmacology"

DOI: 10.1016/j.bcp.2016.11.007

Abstract: Graphical abstract Figure. No Caption available. Abstract Bupropion is a widely used antidepressant and smoking cessation aid and a strong inhibitor of CYP2D6 in vivo. Bupropion is administered as a racemic mixture of R‐ and… read more here.

Keywords: cyp2d6; drug; bupropion metabolites; reversible inhibition ... See more keywords
Photo from wikipedia

Bupropion for postpartum smoking relapse: A remote protocol for a two-arm, double-blind, placebo-controlled randomized clinical trial.

Sign Up to like & get
recommendations! Published in 2021 at "Contemporary clinical trials"

DOI: 10.1016/j.cct.2021.106352

Abstract: Cigarette smoking among postpartum women remains a significant public health problem despite known health risks to women and their newborns. It is estimated that over 50% of women quit smoking during pregnancy but 90% relapse… read more here.

Keywords: trial; smoking relapse; relapse; postpartum ... See more keywords

Bupropion induced hyponatremia: A review of literature

Sign Up to like & get
recommendations! Published in 2017 at "European Psychiatry"

DOI: 10.1016/j.eurpsy.2017.01.1391

Abstract: Introduction For over 20 years, bupropion has been used as an antidepressant by inhibiting the norepinephrine-dopamine reuptake. Hyponatremia is a relatively rare condition that has been associated with the use of antidepressants including selective serotonin… read more here.

Keywords: literature; induced hyponatremia; hyponatremia; bupropion induced ... See more keywords

Evidence of hypoglycemic anhedonia and modulation by bupropion in rats

Sign Up to like & get
recommendations! Published in 2021 at "Pharmacology Biochemistry and Behavior"

DOI: 10.1016/j.pbb.2021.173120

Abstract: BACKGROUND Disorders characterized by dysfunction of glucose metabolism are often comorbid with depression. The current study investigated whether a hypoglycemic state caused by 2-deoxy-D-glucose (2-DG) can result in anhedonic behaviors responsive to stimulation of monoamine… read more here.

Keywords: anhedonia modulation; evidence hypoglycemic; hypoglycemic anhedonia; taste reactivity ... See more keywords
Photo from wikipedia

Are all antidepressants the same? The consumer has a point.

Sign Up to like & get
recommendations! Published in 2022 at "Psychological medicine"

DOI: 10.1017/s0033291722000678

Abstract: BACKGROUND Although a large variety of antidepressants agents (AD) with different mechanisms of action are available, no significant differences in efficacy and safety have been shown. However, there have been few attempts to incorporate data… read more here.

Keywords: medicine; emotional blunting; consumer point; treatment ... See more keywords

Graphene-cobalt hexacyanoferrate modified sensor doped with molecularly imprinted polymer for selective potentiometric determination of bupropion

Sign Up to like & get
recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-16259-z

Abstract: This study presents the first application of a graphene/cobalt hexacyanoferrate composite as an ion-to-electron transducer interlayer for the selective electrochemical determination of bupropion. The composite was prepared by homogeneously dispersing graphene with tween 80 and… read more here.

Keywords: bupropion; graphene; determination bupropion; cobalt hexacyanoferrate ... See more keywords
Photo from archive.org

Mechanistic Approach for Toxic Effects of Bupropion in Primary Rat Hepatocytes.

Sign Up to like & get
recommendations! Published in 2017 at "Drug research"

DOI: 10.1055/s-0042-123034

Abstract: Bupropion is a widely prescribed antidepressant/smoke cessation drug. However, hepatotoxicity is one of its side effects reported in some recipients. The mechanisms by which bupropion induces hepatotoxicity is not clear yet. This experiment was intended… read more here.

Keywords: rat hepatocytes; alpha tos; bupropion; mechanistic approach ... See more keywords

Practice patterns of bupropion co-prescription with antipsychotic medications

Sign Up to like & get
recommendations! Published in 2022 at "Journal of Addictive Diseases"

DOI: 10.1080/10550887.2022.2028531

Abstract: Abstract Objective: Bupropion is one of the few medications with an FDA indication for smoking cessation. This is of particular significance due to the high co-morbidity of tobacco use disorder in patients with schizophrenia spectrum… read more here.

Keywords: antipsychotic medications; practice patterns; bupropion antipsychotic; patterns bupropion ... See more keywords