A highly sensitive and specific method to evaluate viable fungal burden of Aspergillus fumigatus in mice by RT-qPCR for 18S ribosomal RNA.
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DOI: 10.1016/j.mimet.2021.106214
Abstract: Potent fungicidal activity is one of the key factors of antifungals to overcome invasive pulmonary aspergillosis (IPA). To date, quantification of Aspergillus DNA in the lungs and galactomannan (GM) in serum or bronchoalveolar lavage fluid… read more here.
Keywords: 18s ribosomal; viable fungal; method; burden ... See more keywords