One-Year Safety and Effectiveness of Insulin Degludec in Patients with Diabetes Mellitus in Routine Clinical Practice in India—TRUST (Tresiba Real-World Use Study)
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DOI: 10.2337/db18-1019-p
Abstract: Insulin degludec (degludec) is a basal insulin with an ultra-long duration of action and low day-to-day variability in the glucose-lowering effect. The aim of this non-interventional, multicentric, prospective, post-authorization safety study (PASS) was to evaluate… read more here.
Keywords: insulin; bureau self; speaker9s bureau; private limited ... See more keywords
Prevalence of Obesity in the U.S. Adult Population—An Analysis of National Health and Nutrition Examination Surveys, 2003–2012
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DOI: 10.2337/db18-1679-p
Abstract: Obesity is associated with increased CV risk. Using data from National Health and Nutrition Examination Surveys (NHANES; 2003-2012), we estimated frequency and prevalence of obesity in U.S. adults (≥20 years). Participants in 5 NHANES surveys… read more here.
Keywords: obesity; speaker9s bureau; bureau self; prevalence ... See more keywords
Reduced Rate of Acute Complications with Tubeless Insulin Pump Use—Data from 2,640 Patients in the German/Austrian DPV Registry
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DOI: 10.2337/db18-1695-p
Abstract: Little is known about the rates of acute complications when switching from MDI or traditional insulin pumps to tubeless insulin pump therapy. The German/Austrian Diabetes patients follow-up-registry (DPV) includes 2691 patients with type 1 (n=2640),… read more here.
Keywords: pump; insulin; speaker9s bureau; bureau self ... See more keywords
Individual and Combined Glucose-Lowering Effects of Glucagon Receptor Antagonism and Sodium-Glucose Cotransporter 2 Inhibition
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DOI: 10.2337/db18-1942-p
Abstract: Studies suggest that sodium-glucose cotransporter 2 inhibitors (SGLT2i) induce hyperglucagonemia, which might counteract its glucose-lowering ability in type 2 diabetes. In a randomized, placebo-controlled, double-dummy, double-blinded, cross-over study, 12 middle-aged patients with type 2 diabetes… read more here.
Keywords: advisory panel; bureau self; speaker9s bureau; self ... See more keywords
Identification and Analysis of a Novel Glucose Toxicity–Sensitive Gene in Pancreatic ß Cell
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DOI: 10.2337/db18-2144-p
Abstract: Chronic hyperglycemia in type 2 diabetes (T2D) causes pancreatic β-cell dysfunction, which is well known as glucose toxicity (GT), whereas the treatment of T2D improves that dysfunction. However, its underlying molecular mechanism has not yet… read more here.
Keywords: bureau self; research support; speaker9s bureau; support self ... See more keywords
Prevalence and Predictors of Residual Hypertriglyceridemia According to Statin Use in U.S. Adults with Diabetes
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DOI: 10.2337/db18-332-or
Abstract: Background: Hypertriglyceridemia (HTG) is associated with increased cardiovascular risk and is common in diabetes (DM); however, statin therapy remains the primary treatment in most with moderate HTG. We examined the extent of residual HTG despite… read more here.
Keywords: statin use; bureau self; self amarin; speaker9s bureau ... See more keywords
IDegAsp Improves Glycemic Control with Minimal Hypoglycemia—An Indian Real-World Study in T2D Subjects
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DOI: 10.2337/db18-389-p
Abstract: Background: IDegAsp is the first insulin co-formulation constituting 70% insulin degludec and 30% insulin aspart. In contrast to conventional premix analogues, degludec component of IDegAsp lowers variability, fasting glucose with comparable glycemic control and fewer… read more here.
Keywords: t2d subjects; real world; bureau self; speaker9s bureau ... See more keywords
Diabetes Mellitus and High Triglycerides Are Significant Predictors of Major Cardiovascular Events and Increased Health Care Costs and Resource Utilization—A Real-World Analysis of High-Risk Statin-Treated Patients
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DOI: 10.2337/db18-416-p
Abstract: Background: Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of morbidity and mortality in patients with diabetes. We investigated real-world impact of high triglycerides (TG) and diabetes on cardiovascular (CV) outcomes and costs. Methods: This… read more here.
Keywords: real world; bureau self; self amarin; speaker9s bureau ... See more keywords
Are Complications Preventable with Periodic Education via Telemedicine? A Study of 414 Compliant T2D Patients Followed Up for 19 Years
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DOI: 10.2337/db18-685-p
Abstract: Background: Despite availability of many new diabetes therapies, outcomes still remain very poor, with majority developing debilitating vascular complications. Landmark trials have demonstrated, complications could be prevented if patients keep achieving A1c, BP and cholesterol… read more here.
Keywords: none; speaker9s bureau; bureau self;
Total Energy Expenditure Evaluated by Doubly Labeled Water Method in Japanese Patients with Diabetes Mellitus—Clinical Evaluation of Energy Requirements in Patients with Diabetes Mellitus (CLEVER-DM) Study
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DOI: 10.2337/db18-775-p
Abstract: Background and Aim: Assessment of total energy expenditure (TEE) is essential for recommendations for dietary intakes and physical activity in patients with diabetes mellitus as well as healthy people. However, few reports have shown TEE… read more here.
Keywords: patients diabetes; bureau self; energy; speaker9s bureau ... See more keywords
Intervention of the Flash Glucose Sensing Technology on Glycemic Control and Treatment Satisfaction in Patients with Type 2 Diabetes Treated Intensively by Insulin—A Randomized Controlled Trial
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DOI: 10.2337/db18-908-p
Abstract: Objective: To determine the satisfaction from treatment and effectiveness of flash glucose monitoring system (FGM) in patients with type 2 diabetes. Design and Methods: 101 individuals with type 2 diabetes on multiple daily insulin injection… read more here.
Keywords: advisory panel; bureau self; speaker9s bureau; self ... See more keywords