Development of a TaqMan Real‐Time Polymerase Chain Reaction Assay for Detection of Burkholderia mallei
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Equine Veterinary Science"
DOI: 10.1016/j.jevs.2017.08.008
Abstract: Abstract Burkholderia mallei is the causative agent of glanders, a highly contagious and reemerging zoonotic disease. B. mallei is closely related to Burkholderia pseudomallei, the etiologic agent of melioidosis. The genetic proximity between B. mallei… read more here.
Keywords: detection; taqman real; real time; burkholderia mallei ... See more keywords
Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-00173-8
Abstract: Burkholderia pseudomallei (Bp) and Burkholderia mallei (Bm), the etiologic agents of melioidosis and glanders, respectively, cause severe disease in both humans and animals. Studies have highlighted the importance of Bp and Bm lipopolysaccharides (LPS) as… read more here.
Keywords: pseudomallei burkholderia; deciphering minimal; antigenic epitopes; burkholderia mallei ... See more keywords
Multicomponent gold nano-glycoconjugate as a highly immunogenic and protective platform against Burkholderia mallei
Sign Up to like & getrecommendations! Published in 2020 at "NPJ Vaccines"
DOI: 10.1038/s41541-020-00229-9
Abstract: Burkholderia mallei (Bm) is a facultative intracellular pathogen and the etiological agent of glanders, a highly infectious zoonotic disease occurring in equines and humans. The intrinsic resistance to antibiotics, lack of specific therapy, high mortality,… read more here.
Keywords: burkholderia mallei; highly immunogenic; antigen; vaccine ... See more keywords
Validation of a Lateral Flow Test for the Presumptive Identification of the Presence of Burkholderia mallei or Burkholderia pseudomallei in Environmental Samples.
Sign Up to like & getrecommendations! Published in 2022 at "Health security"
DOI: 10.1089/hs.2021.0168
Abstract: We conducted a comprehensive, multiphase laboratory evaluation of InBios Active Melioidosis Detect (AMD) rapid test, a lateral flow immunoassay designed to detect capsular polysaccharides produced by Burkholderia mallei or Burkholderia pseudomallei, used in conjunction with… read more here.
Keywords: lateral flow; pseudomallei; test; burkholderia mallei ... See more keywords
Rapid Presumptive Identification of Burkholderia mallei and Burkholderia pseudomallei Clinical Isolates Using a Highly Specific Lateral Flow Assay.
Sign Up to like & getrecommendations! Published in 2022 at "Health security"
DOI: 10.1089/hs.2021.0172
Abstract: We conducted a comprehensive, multiphase laboratory evaluation of the InBios Active Melioidosis Detect (AMD) rapid test, a lateral flow immunoassay designed to detect capsular polysaccharides produced by Burkholderia mallei or Burkholderia pseudomallei, used in conjunction… read more here.
Keywords: presumptive identification; burkholderia mallei; lateral flow; identification ... See more keywords
Innate immune response to Burkholderia mallei
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Infectious Diseases"
DOI: 10.1097/qco.0000000000000362
Abstract: Purpose of review Burkholderia mallei is a facultative intracellular pathogen that causes the highly contagious and often the fatal disease, glanders. With its high rate of infectivity via aerosol and recalcitrance toward antibiotics, this pathogen… read more here.
Keywords: immune response; innate immune; burkholderia mallei; response ... See more keywords
Development of a rapid and sensitive recombinase polymerase amplification‐lateral flow assay for detection of Burkholderia mallei
Sign Up to like & getrecommendations! Published in 2019 at "Transboundary and Emerging Diseases"
DOI: 10.1111/tbed.13126
Abstract: Burkholderia mallei, a potential biothreat agent is the aetiological agent of glanders, a zoonotic disease primarily affecting equines. B. mallei shares close genetic proximity with B. pseudomallei, the aetiological agent of melioidosis. Hence, molecular detection… read more here.
Keywords: detection; polymerase amplification; burkholderia mallei; amplification lateral ... See more keywords
Evaluation of Burkholderia mallei ΔtonB Δhcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0007578
Abstract: Background Glanders caused by Burkholderia mallei is a re-emerging zoonotic disease affecting solipeds and humans. Furthermore, B. mallei is genetically related to B. pseudomallei, which is the causative agent of melioidosis. Both facultative intracellular bacteria… read more here.
Keywords: glanders melioidosis; attenuated vaccine; burkholderia mallei; clh001 ... See more keywords
Genetic diversity and spatial distribution of Burkholderia mallei by core genome-based multilocus sequence typing analysis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0270499
Abstract: Burkholderia mallei is the etiological agent of glanders, a highly contagious and often fatal disease in equids. Due to the high genetic clonality of B. mallei, high-resolution typing assays are necessary to differentiate between individual… read more here.
Keywords: core genome; sequence typing; burkholderia mallei; genome based ... See more keywords
Sequencing-Based Genotyping of Pakistani Burkholderia mallei Strains: A Useful Way for Investigating Glanders Outbreaks
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11060614
Abstract: Burkholderia (B.) mallei is a host-adapted equine pathogen that causes glanders, a re-emerging zoonotic disease, which is endemic in Pakistan and other developing countries and seriously impacts the global equine movement. Due to globalization, the… read more here.
Keywords: burkholderia mallei; based genotyping; genotyping pakistani; sequencing based ... See more keywords
Computational Based Designing of a Multi-Epitopes Vaccine against Burkholderia mallei
Sign Up to like & getrecommendations! Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines10101580
Abstract: The emergence of antibiotic resistance in bacterial species is a major threat to public health and has resulted in high mortality as well as high health care costs. Burkholderia mallei is one of the etiological… read more here.
Keywords: burkholderia mallei; multi epitopes; epitopes vaccine; kcal mol ... See more keywords