A unique AA5 alcohol oxidase fused with a catalytically inactive CE3 domain from the bacterium Burkholderia pseudomallei.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS letters"
DOI: 10.1002/1873-3468.14632
Abstract: Copper radical oxidases (CROs) are redox enzymes able to oxidize alcohols or aldehydes, while only requiring a single copper atom as cofactor. Studied CROs are found in one of two subfamilies within the Auxiliary Activities… read more here.
Keywords: alcohol oxidase; burkholderia pseudomallei; domain;
Immunoassay using dendritic Au-Pt nanoparticles as signal labels for detection of the biomarker of Burkholderia pseudomallei
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Nanoparticle Research"
DOI: 10.1007/s11051-020-05054-8
Abstract: In this work, the peroxidase-like properties of dendritic Au-Pt nanoparticles (30~60 nm) were investigated and these nanoparticles were applied in the immunoassay as signal labels for the detection of capsular polysaccharides (CPS, ~ 300 kDa, expressed… read more here.
Keywords: labels detection; detection; signal labels; cps ... See more keywords
Jugular Lymphadenitis as a Precursor to Burkholderia Pseudomallei Sepsis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Maxillofacial and Oral Surgery"
DOI: 10.1007/s12663-020-01333-y
Abstract: Melioidosis is caused by the gram-negative environmental saprophyte, Burkholderia pseudomallei (B. pseudomallei). Common presentations include pneumonia, bone and joint disease, renal and soft tissue infections. However, head and neck involvement is rare. We report a… read more here.
Keywords: lymphadenitis precursor; burkholderia; precursor burkholderia; burkholderia pseudomallei ... See more keywords
Polymicrobial community-acquired Acinetobacter baumannii and Burkholderia pseudomallei bacteremia: opportunistic infections with similar risk factors in northern Australia
Sign Up to like & getrecommendations! Published in 2020 at "IDCases"
DOI: 10.1016/j.idcr.2020.e00833
Abstract: We report the case of a 61-year-old man from northern Australia with concurrent community-onset Acinetobacter baumannii complex and Burkholderia pseudomallei bacteremia presenting as severe tropical pneumonia requiring intensive care unit support. The pneumonia was complicated… read more here.
Keywords: risk; risk factors; northern australia; acinetobacter baumannii ... See more keywords
Burkholderia pseudomallei acquired ceftazidime resistance due to gene duplication and amplification.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2019.01.003
Abstract: Ceftazidime (CAZ) is the antibiotic of choice for the treatment of Burkholderia pseudomallei infection (melioidosis). The chromosomally-encoded PenA β-lactamase possesses weak cephalosporinase activity. The wild-type penA gene confers clinically significant CAZ resistance only when overexpressed… read more here.
Keywords: gene duplication; resistance; pseudomallei; gene ... See more keywords
Virulence from the rhizosphere: ecology and evolution of Burkholderia pseudomallei-complex species.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in microbiology"
DOI: 10.1016/j.mib.2019.12.004
Abstract: Burkholderia pseudomallei (Bp) and Burkholderia mallei (Bm) cause the often-lethal infectious diseases melioidosis and glanders, respectively. Curiously, closely related species within the Bp complex share a nearly identical arsenal of virulence traits, yet are harmless… read more here.
Keywords: virulence rhizosphere; virulence; ecology evolution; rhizosphere ecology ... See more keywords
Biomarker discovery in the biofilm-forming process of Burkholderia pseudomallei by mass-spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2019.02.011
Abstract: A serious human infectious disease called Melioidosis is a result of Burkholderia pseudomallei infection. Treatment for infected individuals is difficult due to a wide range of ineffective antibiotics including a high level of antibiotic tolerance… read more here.
Keywords: burkholderia pseudomallei; biofilm; mass spectrometry; biofilm forming ... See more keywords
First report of Burkholderia pseudomallei ST412 and ST734 clones harbouring blaOXA-57 but susceptible to imipenem in India
Sign Up to like & getrecommendations! Published in 2019 at "New Microbes and New Infections"
DOI: 10.1016/j.nmni.2019.100613
Abstract: Melioidosis caused by Burkholderia pseudomallei has become an important clinical threat, especially in Northern Australia and Southeast Asia. However, the genome information on this pathogen is limited. B. pseudomallei isolates identified from bloodstream infections from… read more here.
Keywords: susceptible imipenem; pseudomallei st412; report burkholderia; blaoxa ... See more keywords
Phylogenetic Diversity of Burkholderia pseudomallei isolated from veterinary cases and the environments in Peninsular Malaysia
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary and Animal Science"
DOI: 10.1016/j.vas.2018.07.004
Abstract: This study was designed to determine the genotype and the phylogeny of Burkholderia pseudomallei isolated from veterinary cases and from the animal environments in Peninsular Malaysia. The Malaysian B. pseudomallei population were then compared to… read more here.
Keywords: malaysia; pseudomallei isolated; veterinary cases; pseudomallei ... See more keywords
Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-00173-8
Abstract: Burkholderia pseudomallei (Bp) and Burkholderia mallei (Bm), the etiologic agents of melioidosis and glanders, respectively, cause severe disease in both humans and animals. Studies have highlighted the importance of Bp and Bm lipopolysaccharides (LPS) as… read more here.
Keywords: pseudomallei burkholderia; deciphering minimal; antigenic epitopes; burkholderia mallei ... See more keywords
Burkholderia pseudomallei OMVs derived from infection mimicking conditions elicit similar protection to a live-attenuated vaccine
Sign Up to like & getrecommendations! Published in 2021 at "NPJ Vaccines"
DOI: 10.1038/s41541-021-00281-z
Abstract: Burkholderia pseudomallei is a Gram-negative, facultative intracellular bacillus that causes the disease melioidosis. B. pseudomallei expresses a number of proteins that contribute to its intracellular survival in the mammalian host. We previously demonstrated that immunization… read more here.
Keywords: attenuated vaccine; burkholderia pseudomallei; live attenuated; vaccine ... See more keywords