Busulfan-based reduced toxicity conditioning regimen used in hematopoietic stem cell transplantation in HLH patients results in sustained donor chimerism
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DOI: 10.1080/08880018.2020.1868638
Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a severe systemic inflammatory syndrome characterized by excessive inflammation and an ineffective immune response. This syndrome, often driven by a genetic abnormality, can ultimately be fatal if unsuccessfully controlled. Allogeneic hematopoietic… read more here.
Keywords: busulfan based; hlh patients; conditioning regimen; hematopoietic stem ... See more keywords
Long-Term Outcomes of Treosulfan- vs. Busulfan-Based Conditioning Regimen for Patients With Myelodysplastic Syndrome and Acute Myeloid Leukemia Before Hematopoietic Cell Transplantation: A Systematic Review and Meta-Analysis
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DOI: 10.3389/fonc.2020.591363
Abstract: Background Many studies aimed to evaluate the efficacy and safety of treosulfan-based conditioning regimens for allogeneic hematopoietic cell transplantation (allo-HCT) compared with other regimens, but different outcomes were reported across studies. Aim To determine the… read more here.
Keywords: acute; treosulfan based; busulfan based; based conditioning ... See more keywords