Theoretical study on mechanism of reaction between tert-butyl isocyanide and dimethyl acetylenedicarboxylate in presence of ethanethiol or thiophenol
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DOI: 10.1007/s11164-018-3252-0
Abstract: The mechanism of the multicomponent reaction between tert-butyl isocyanide and dimethyl acetylenedicarboxylate in presence of ethanethiol and thiophenol (as SH-acid) was investigated theoretically. According to quantum-mechanical computations, four different pathways (I, II, III, and IV)… read more here.
Keywords: mechanism; butyl isocyanide; tert butyl; reaction ... See more keywords
Palladium-Catalyzed Synthesis of Amidines via tert-Butyl isocyanide Insertion
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DOI: 10.1021/acsomega.8b02010
Abstract: Para-substituted iodobenzenes were reacted with tert-butyl isocyanide and piperidine as nucleophiles in the presence of palladium–diphosphine catalysts. Both single and double insertion of the isocyanide was observed and the corresponding amidines and ketimine–amidines were obtained… read more here.
Keywords: insertion; palladium catalyzed; tert butyl; butyl isocyanide ... See more keywords