L-3-n-Butylphthalide reduces ischemic stroke injury and increases M2 microglial polarization
Sign Up to like & getrecommendations! Published in 2018 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-018-0307-2
Abstract: Overwhelming evidence suggests that microglia play an important role in ischemic injury and they polarize into two different phenotypes with distinct functions after ischemic stroke. We performed the present study to investigate whether L-3-n butylphthalide… read more here.
Keywords: microglial polarization; ischemic stroke; butylphthalide; days mcao ... See more keywords
From Seeds of Apium graveolens Linn. to a Cerebral Ischemia Medicine: The Long Journey of 3-n-Butylphthalide.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.0c00887
Abstract: 3-n-Butylphthalide (NBP) as well as its derivatives and analogues (NBPs), in racemic or enantiomerically pure forms, possess potent and diverse pharmacological properties, and have shown a great potential therapeutic interest for many human conditions, especially… read more here.
Keywords: medicine; butylphthalide; cerebral ischemia; seeds apium ... See more keywords