Articles with "butyrate" as a keyword



Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population

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Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202411086

Abstract: Gut microbiota is essential for the function of peripherally‐induced regulatory T (pTreg) cells. However, how commensal bacteria affect thymically derived fat‐resident Treg cells that harbor a unique expression of peroxisome proliferator‐activated receptor (PPAR)‐γ and suppress… read more here.

Keywords: ppar; gut microbiota; population; butyrate ... See more keywords

Faecalibaculum rodentium Alleviates Ionizing Radiation-Induced Damage in Mice by Improving Intestinal Integrity and Hematopoiesis via Its Metabolite Butyrate.

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Published in 2025 at "Advanced science"

DOI: 10.1002/advs.202509383

Abstract: The gut microbiota is key to mitigating ionizing radiation (IR)–induced injuries; however, the specific species involved in and the molecular mechanisms remain elusive. Mitochondrial dynamics affect gut microbiota diversity. To identify the specific species involved… read more here.

Keywords: radiation induced; butyrate; rodentium; faecalibaculum rodentium ... See more keywords

CRISPR interference-mediated metabolic engineering of Corynebacterium glutamicum for homo-butyrate production.

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Published in 2018 at "Biotechnology and bioengineering"

DOI: 10.1002/bit.26720

Abstract: Combinatorial metabolic engineering enabled the development of efficient microbial cell factories for modulating gene expression to produce desired products. Here, we report the combinatorial metabolic engineering of Corynebacterium glutamicum to produce butyrate by introducing a… read more here.

Keywords: production; butyrate; metabolic engineering; glutamicum ... See more keywords

Synergistic Effects of Riluzole and Sodium Butyrate on Barrier Function and Disease Progression of Amyotrophic Lateral Sclerosis Through the Gut‐Neuron Axis

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Published in 2025 at "Comprehensive Physiology"

DOI: 10.1002/cph4.70009

Abstract: Emerging evidence has shown that gut‐brain barrier dysfunction occurs at the early stages of ALS. Previous studies demonstrated that sodium butyrate significantly prolonged the life span of ALS mice. Riluzole is the first FDA‐approved drug… read more here.

Keywords: treatment; sodium butyrate; riluzole sodium; barrier ... See more keywords

The macroecology of butyrate‐producing bacteria via metagenomic assessment of butyrate production capacity

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Published in 2024 at "Ecology and Evolution"

DOI: 10.1002/ece3.11239

Abstract: Abstract Butyrate‐producing bacteria are found in many outdoor ecosystems and host organisms, including humans, and are vital to ecosystem functionality and human health. These bacteria ferment organic matter, producing the short‐chain fatty acid butyrate. However,… read more here.

Keywords: butyrate production; butyrate producing; soil; butyrate ... See more keywords

Butyrate-Loaded Chitosan/Hyaluronan Nanoparticles: A Suitable Tool for Sustained Inhibition of ROS Release by Activated Neutrophils.

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Published in 2017 at "Macromolecular bioscience"

DOI: 10.1002/mabi.201700214

Abstract: Tissue damage caused by excessive amounts of neutrophil-derived reactive oxygen species (ROS) occurs in many inflammatory diseases. Butyrate is a short-chain fatty acid (SCFA) with known anti-inflammatory properties, able to modulate several neutrophil functions. Evidence… read more here.

Keywords: ros release; chitosan hyaluronan; hyaluronan nanoparticles; butyrate ... See more keywords

Butyrate Modification Promotes Intestinal Absorption and Hepatic Cancer Cells Targeting of Ferroptosis Inducer Loaded Nanoparticle for Enhanced Hepatocellular Carcinoma Therapy.

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Published in 2023 at "Small"

DOI: 10.1002/smll.202301149

Abstract: Sorafenib is an oral-administered first-line drug for hepatocellular carcinoma (HCC) treatment. However, the therapeutic efficacy of sorafenib is relatively low. Here, an oral delivery platform that increases sorafenib uptake by HCC and induces potent ferroptosis… read more here.

Keywords: hepatocellular carcinoma; hcc; butyrate; ferroptosis ... See more keywords

Neryl butyrate induces contractile effects on isolated preparations of rat aorta

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Published in 2019 at "Naunyn-Schmiedeberg's Archives of Pharmacology"

DOI: 10.1007/s00210-019-01709-z

Abstract: Neryl butyrate is a constituent of volatile oils obtained from aromatic plants. Aliphatic organic compound analogues chemically close to neryl butyrate possess vasodilator properties in rat aorta. To evaluate whether neryl butyrate has relaxing properties,… read more here.

Keywords: effects isolated; butyrate; rat aorta; contraction ... See more keywords

Microbial production of butyl butyrate, a flavor and fragrance compound

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Published in 2018 at "Applied Microbiology and Biotechnology"

DOI: 10.1007/s00253-018-09603-z

Abstract: Butyl butyrate (BB) has been widely used as a flavor and fragrance compound in the beverage, food, perfume, and cosmetic industries. Currently, BB is produced through two-step processes; butanol and butyrate are first produced and… read more here.

Keywords: production; butyrate; flavor fragrance; fragrance compound ... See more keywords

Open microbiome dominated by Clostridium and Eubacterium converts methanol into i-butyrate and n-butyrate

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Published in 2020 at "Applied Microbiology and Biotechnology"

DOI: 10.1007/s00253-020-10551-w

Abstract: Isobutyrate (i-butyrate) is a versatile platform chemical, whose acid form is used as a precursor of plastic and emulsifier. It can be produced microbially either using genetically engineered organisms or via microbiomes, in the latter… read more here.

Keywords: clostridium eubacterium; butyrate butyrate; production; butyrate ... See more keywords

Butyrate inhibits the malignant biological behaviors of breast cancer cells by facilitating cuproptosis-associated gene expression

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Published in 2024 at "Journal of Cancer Research and Clinical Oncology"

DOI: 10.1007/s00432-024-05807-1

Abstract: Background Butyrate is a common short-chain fatty acids (SCFA), and it has been demonstrated to regulate the development of breast cancer (BC), while the underlying mechanism is still unreported. Methods Gas chromatography was used to… read more here.

Keywords: breast cancer; malignant biological; cuproptosis; butyrate ... See more keywords