Exploiting heterologous and endogenous CRISPR‐Cas systems for genome editing in the probiotic Clostridium butyricum
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27753
Abstract: Clostridium butyricum has been widely used as a probiotic for humans and food animals. However, the mechanisms of beneficial effects of C. butyricum on the host remain poorly understood, largely due to the lack of… read more here.
Keywords: genome editing; butyricum; crispr; crispr cas ... See more keywords
Establishment and evaluation of a method for efficient screening of Clostridium butyricum
Sign Up to like & getrecommendations! Published in 2020 at "Folia Microbiologica"
DOI: 10.1007/s12223-020-00803-7
Abstract: At present, the traditional methods for the screening of Clostridium butyricum are not sufficiently selective and efficient. Therefore, it is necessary to establish a targeted and efficient screening method for the detection of C. butyricum.… read more here.
Keywords: clostridium butyricum; butyricum; efficient screening; screening clostridium ... See more keywords
Clostridium butyricum relieves diarrhea by enhancing digestive function, maintaining intestinal barrier integrity, and relieving intestinal inflammation in weaned piglets
Sign Up to like & getrecommendations! Published in 2020 at "Livestock Science"
DOI: 10.1016/j.livsci.2020.104112
Abstract: Abstract The current study aimed to determine how Clostridium butyricum (C. butyricum) relieved diarrhea by evaluating its effects on intestinal digestive enzyme activity, barrier integrity, inflammatory responses, and oxidative stress in weaned piglets. A total… read more here.
Keywords: butyricum; barrier integrity; group; weaned piglets ... See more keywords
Clostridium butyricum inhibits epithelial-mesenchymal transition of intestinal carcinogenesis through downregulating METTL3.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer science"
DOI: 10.1093/ecco-jcc/jjac190.1048
Abstract: Colorectal cancer (CRC) is related to gut microbiota dysbiosis, especially butyrate-producing bacteria reduction. Our previous study suggested that administration of Clostridium butyricum, a butyrate-producing bacterium, exerts a crucial effect against CRC, however the potential mechanism… read more here.
Keywords: mesenchymal transition; crc; butyricum; epithelial mesenchymal ... See more keywords
Inclusion of the direct-fed microbial Clostridium butyricum in diets for weanling pigs increases growth performance and tends to increase villus height and crypt depth, but does not change intestinal microbial abundance.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of animal science"
DOI: 10.1093/jas/skz372
Abstract: An experiment was conducted to test the hypothesis that inclusion of the direct fed microbial Clostridium butyricum in diets for weanling pigs will improve growth performance, systemic immune function, microbiota composition, and gut morphology in… read more here.
Keywords: villus height; butyricum; crypt depth; pigs fed ... See more keywords
Oral administration of Clostridium butyricum CGMCC0313‐1 reduces ovalbumin‐induced allergic airway inflammation in mice
Sign Up to like & getrecommendations! Published in 2017 at "Respirology"
DOI: 10.1111/resp.12985
Abstract: Probiotic bacteria can induce immune regulation or immune tolerance in patients with allergic diseases, but the underlying mechanisms are still unclear. There has been a growing interest in the use of beneficial bacteria for allergic… read more here.
Keywords: clostridium butyricum; allergic airway; butyricum; butyricum cgmcc0313 ... See more keywords
Protective Effect of Clostridium butyricum on Escherichia coli-Induced Endometritis in Mice via Ameliorating Endometrial Barrier and Inhibiting Inflammatory Response
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03286-22
Abstract: Endometritis is a common reproductive disease both in human and animals. It impairs female fertility by disrupting endometrial function. Antibiotics are widely used to treat endometritis in clinical practice, but the misuse of antibiotics often… read more here.
Keywords: induced endometritis; protective effect; butyricum; endometritis ... See more keywords
Clostridium butyricum partially regulates the development of colitis-associated cancer through miR-200c.
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2017.63.4.10
Abstract: Colitis-associated cancer (CAC), one form of colorectal cancer (CRC),is an increasing concern worldwide. Both diagnosis and current therapy are challenging and bottlenecked. The aim of this study is to investigate novel mechanisms by which the… read more here.
Keywords: associated cancer; butyricum; mir 200c; colitis associated ... See more keywords
Clostridium butyricum Induces the Production and Glycosylation of Mucins in HT-29 Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.668766
Abstract: C. butyricum is a common gut commensal bacterium, which has many positive functions in human intestine. In this study, we investigated the effects of monosaccharide and its derivatives on the adhesion of C. butyricum to… read more here.
Keywords: glycosylation mucins; butyricum; production; butyricum cells ... See more keywords
Clostridium butyricum potentially improves inflammation and immunity through alteration of the microbiota and metabolism of gastric cancer patients after gastrectomy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1076245
Abstract: Background Gastrectomy is the most effective treatment to improve the clinical survival rate of patients with gastric cancer. However, the pathophysiological changes caused by gastrectomy have seriously affected the postoperative recovery. Methods In the present… read more here.
Keywords: immunity; patients gastrectomy; acid; butyricum ... See more keywords
Clostridium butyricum alleviates LPS-induced acute immune stress in goats by regulating bacterial communities and blood metabolites
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1099186
Abstract: The mitigation and prevention of acute immune stress are essential for livestock production. Clostridium butyricum (C. butyricum) has shown positive effects in stabilizing intestinal microbiota disorders, improving immune function and inhibiting disease development, but its… read more here.
Keywords: immune stress; bacterial communities; butyricum; acute immune ... See more keywords