Exploiting heterologous and endogenous CRISPR‐Cas systems for genome editing in the probiotic Clostridium butyricum
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27753
Abstract: Clostridium butyricum has been widely used as a probiotic for humans and food animals. However, the mechanisms of beneficial effects of C. butyricum on the host remain poorly understood, largely due to the lack of… read more here.
Keywords: genome editing; butyricum; crispr; crispr cas ... See more keywords
The Effect of Clostridium butyricum‐Derived Lipoteichoic Acid on Lipopolysaccharide‐Stimulated Porcine Intestinal Epithelial Cells
Sign Up to like & getrecommendations! Published in 2025 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.70157
Abstract: ABSTRACT Background Clostridium butyricum is a probiotic widely used in animal husbandry, and there is evidence to suggest that it can alleviate intestinal inflammation in pigs and may be related to its lipoteichoic acid (LTA),… read more here.
Keywords: tnf; lta; gene expression; butyricum ... See more keywords
Flavonoid-converting capabilities of Clostridium butyricum
Sign Up to like & getrecommendations! Published in 2025 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-025-13434-0
Abstract: Clostridium butyricum inhabits various anoxic environments, including soil and the human gut. Here, this common bacterium comes into contact with abundant plant-derived flavonoids. Metabolization of these bioactive polyphenols has been studied in recent years, particularly… read more here.
Keywords: flavonoid converting; clostridium butyricum; butyricum; capabilities clostridium ... See more keywords
Establishment and evaluation of a method for efficient screening of Clostridium butyricum
Sign Up to like & getrecommendations! Published in 2020 at "Folia Microbiologica"
DOI: 10.1007/s12223-020-00803-7
Abstract: At present, the traditional methods for the screening of Clostridium butyricum are not sufficiently selective and efficient. Therefore, it is necessary to establish a targeted and efficient screening method for the detection of C. butyricum.… read more here.
Keywords: clostridium butyricum; butyricum; efficient screening; screening clostridium ... See more keywords
Clostridium butyricum relieves diarrhea by enhancing digestive function, maintaining intestinal barrier integrity, and relieving intestinal inflammation in weaned piglets
Sign Up to like & getrecommendations! Published in 2020 at "Livestock Science"
DOI: 10.1016/j.livsci.2020.104112
Abstract: Abstract The current study aimed to determine how Clostridium butyricum (C. butyricum) relieved diarrhea by evaluating its effects on intestinal digestive enzyme activity, barrier integrity, inflammatory responses, and oxidative stress in weaned piglets. A total… read more here.
Keywords: butyricum; barrier integrity; group; weaned piglets ... See more keywords
Clostridium butyricum inhibits epithelial-mesenchymal transition of intestinal carcinogenesis through downregulating METTL3.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer science"
DOI: 10.1093/ecco-jcc/jjac190.1048
Abstract: Colorectal cancer (CRC) is related to gut microbiota dysbiosis, especially butyrate-producing bacteria reduction. Our previous study suggested that administration of Clostridium butyricum, a butyrate-producing bacterium, exerts a crucial effect against CRC, however the potential mechanism… read more here.
Keywords: mesenchymal transition; crc; butyricum; epithelial mesenchymal ... See more keywords
Inclusion of the direct-fed microbial Clostridium butyricum in diets for weanling pigs increases growth performance and tends to increase villus height and crypt depth, but does not change intestinal microbial abundance.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of animal science"
DOI: 10.1093/jas/skz372
Abstract: An experiment was conducted to test the hypothesis that inclusion of the direct fed microbial Clostridium butyricum in diets for weanling pigs will improve growth performance, systemic immune function, microbiota composition, and gut morphology in… read more here.
Keywords: villus height; butyricum; crypt depth; pigs fed ... See more keywords
Comparative genomics of Clostridium butyricum reveals a conserved genome architecture and novel virulence-related gene clusters
Sign Up to like & getrecommendations! Published in 2025 at "Microbial Genomics"
DOI: 10.1099/mgen.0.001477
Abstract: Abstract Bacteria from the species Clostridium butyricum encompass a diverse range of phenotypes. While some strains are used as probiotics, others have been isolated from cases of botulism and necrotizing enterocolitis (NEC) in preterm neonates.… read more here.
Keywords: genomics clostridium; clostridium butyricum; virulence; comparative genomics ... See more keywords
Oral administration of Clostridium butyricum CGMCC0313‐1 reduces ovalbumin‐induced allergic airway inflammation in mice
Sign Up to like & getrecommendations! Published in 2017 at "Respirology"
DOI: 10.1111/resp.12985
Abstract: Probiotic bacteria can induce immune regulation or immune tolerance in patients with allergic diseases, but the underlying mechanisms are still unclear. There has been a growing interest in the use of beneficial bacteria for allergic… read more here.
Keywords: clostridium butyricum; allergic airway; butyricum; butyricum cgmcc0313 ... See more keywords
Protective Effect of Clostridium butyricum on Escherichia coli-Induced Endometritis in Mice via Ameliorating Endometrial Barrier and Inhibiting Inflammatory Response
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03286-22
Abstract: Endometritis is a common reproductive disease both in human and animals. It impairs female fertility by disrupting endometrial function. Antibiotics are widely used to treat endometritis in clinical practice, but the misuse of antibiotics often… read more here.
Keywords: induced endometritis; protective effect; butyricum; endometritis ... See more keywords
Clostridium butyricum inhibits the inflammation in children with primary nephrotic syndrome by regulating Th17/Tregs balance via gut-kidney axis
Sign Up to like & getrecommendations! Published in 2024 at "BMC Microbiology"
DOI: 10.1186/s12866-024-03242-3
Abstract: Background Primary nephrotic syndrome (PNS) is a common glomerular disease in children. Clostridium butyricum ( C. butyricum), a probiotic producing butyric acid, exerts effective in regulating inflammation. This study was designed to elucidate the effect… read more here.
Keywords: kidney axis; butyricum; pns; inflammation ... See more keywords