Structure‐Activity Relationships of Butyrophilin 3 Ligands
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DOI: 10.1002/cmdc.202000198
Abstract: Phosphoantigens (pAgs) are small phosphorus‐containing molecules that stimulate Vγ9Vδ2 T cells with sub‐nanomolar cellular potency. Recent work has revealed that these compounds work through binding to the transmembrane immunoglobulin butyrophilin 3A1 (BTN3A1) within its intracellular… read more here.
Keywords: activity relationships; relationships butyrophilin; structure activity; butyrophilin ligands ... See more keywords