Controlling selectivity of modular microbial biosynthesis of butyryl-CoA-derived designer esters.
Sign Up to like & getrecommendations! Published in 2021 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2021.12.001
Abstract: Short-chain esters have broad utility as flavors, fragrances, solvents, and biofuels. Controlling selectivity of ester microbial biosynthesis has been an outstanding metabolic engineering problem. Here, we present a generalizable framework to enable the de novo… read more here.
Keywords: coa; designer esters; selectivity; production ... See more keywords
Biosynthesis of Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) From Glucose by Escherichia coli Through Butyryl-CoA Formation Driven by Ccr-Emd Combination
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.888973
Abstract: Poly[(R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate] [P(3HB-co-3HHx)] is a practical kind of bacterial polyhydroxyalkanoates (PHAs). A previous study has established an artificial pathway for the biosynthesis of P(3HB-co-3HHx) from structurally unrelated sugars in Ralstonia eutropha, in which crotonyl-CoA carboxylase/reductase (Ccr)… read more here.
Keywords: hydroxybutyrate hydroxyhexanoate; butyryl coa; escherichia coli; coa ... See more keywords