Pinitol Prevents Lipopolysaccharide (LPS)-Induced Inflammatory Responses in BV2 Microglia Mediated by TREM2
Sign Up to like & getrecommendations! Published in 2020 at "Neurotoxicity Research"
DOI: 10.1007/s12640-020-00187-z
Abstract: Microglia-involved neuroinflammation in the central nervous system (CNS) has been shown to aggravate brain damage and is associated with the pathogenesis of various neurodegenerative diseases. Thus, suppression of microglial activity has the potential to be… read more here.
Keywords: trem2; inflammatory responses; lps induced; pinitol prevents ... See more keywords
Mirtazapine prevents cell activation, inflammation, and oxidative stress against isoflurane exposure in microglia
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2009971
Abstract: ABSTRACT Mirtazapine is an antidepressant drug that has been proven to possess a cognitive enhancer efficiency. In this study, we evaluated the potential protective effects of mirtazapine on BV2 microglia in response to isoflurane exposure.… read more here.
Keywords: isoflurane; activation; mirtazapine; bv2 microglia ... See more keywords
Longxuetongluo capsule alleviates LPS-induced neuro-inflammation by regulating multiple signaling pathways in BV2 microglia cells.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Chinese Medical Association"
DOI: 10.1097/jcma.0000000000000258
Abstract: BACKGROUND Longxuetongluo capsule (LTC), derived from the total phenolic compounds of Chinese dragon's blood, is now used to treatment of ischemic stroke in convalescence. The aim of this study is to explore the neuroprotective effect… read more here.
Keywords: microglia cells; longxuetongluo capsule; bv2 microglia; signaling pathways ... See more keywords
Anti-inflammatory effects of vinpocetine in LPS-stimulated microglia via activation of AMPK.
Sign Up to like & getrecommendations! Published in 2020 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765202020200241
Abstract: Microglia are the resident immune cells in the central nervous system (CNS), which play important roles in the repair of neuroinflammatory injury. The present study investigated the anti-neuroinflammatory effects of vinpocetine induced by lipopolysaccharide (LPS)… read more here.
Keywords: anti inflammatory; lps stimulated; effects vinpocetine; microglia via ... See more keywords
Taraxasterol Inhibits LPS-Induced Inflammatory Response in BV2 Microglia Cells by Activating LXRα
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.00278
Abstract: Neuroinflammation plays a critical role in the development of neurodegenerative diseases. Taraxasterol, a pentacyclic-triterpene isolated from Taraxacum officinale, has been reported to have anti-inflammatory effect. The aim of this study was to investigate the anti-inflammatory… read more here.
Keywords: lps induced; microglia cells; inhibits lps; taraxasterol ... See more keywords
6-Hydroxydopamine Induces Abnormal Iron Sequestration in BV2 Microglia by Activating Iron Regulatory Protein 1 and Inhibiting Hepcidin Release
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12020266
Abstract: Disrupted iron homeostasis in the substantia nigra pars compacta (SNpc) is an important pathological mechanism in Parkinson’s disease (PD). It is unclear what role microglia play in iron metabolism and selective iron deposition in the… read more here.
Keywords: iron; iron regulatory; expression; release ... See more keywords
Small Extracellular Vesicles of M1-BV2 Microglia Induce Neuronal PC12 Cells Apoptosis via the Competing Endogenous Mechanism of CircRNAs
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13091603
Abstract: Polarized microglia play a vital role in neurodegenerative diseases. However, the effects of polarized microglia-derived small extracellular vesicles (SEVs) on neuronal cells and the regulatory mechanisms of circular RNAs (circRNAs) in SEVs remain incompletely defined.… read more here.
Keywords: neuronal pc12; circ; pc12 cells; bv2 microglia ... See more keywords
Cannabisin F from Hemp (Cannabis sativa) Seed Suppresses Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglia as SIRT1 Modulator
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20030507
Abstract: Hemp seed (Fructus cannabis) is rich in lignanamides, and initial biological screening tests showed their potential anti-inflammatory and anti-oxidative capacity. This study investigated the possible effects and underlying mechanism of cannabisin F, a hempseed lignanamide,… read more here.
Keywords: cannabis; seed; cannabisin; factor ... See more keywords
Spirulina platensis Suppressed iNOS and Proinflammatory Cytokines in Lipopolysaccharide-Induced BV2 Microglia
Sign Up to like & getrecommendations! Published in 2022 at "Metabolites"
DOI: 10.3390/metabo12111147
Abstract: The disease burden of neurodegenerative diseases is on the rise due to the aging population, and neuroinflammation is one of the underlying causes. Spirulina platensis is a well-known superfood with numerous reported bioactivities. However, the… read more here.
Keywords: induced bv2; ethanol extract; cytokines lipopolysaccharide; platensis ... See more keywords
Angelicae Gigantis Radix Regulates LPS-Induced Neuroinflammation in BV2 Microglia by Inhibiting NF-κB and MAPK Activity and Inducing Nrf-2 Activity
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24203755
Abstract: Angelicae Gigantis Radix (AGR) has been widely used as a traditional medicine in East Asia. The effects of AGR on neuroinflammation have not previously been studied in detail. In the study presented here, we investigated… read more here.
Keywords: neuroinflammation; gigantis radix; angelicae gigantis; bv2 microglia ... See more keywords
Catalpol attenuates lipopolysaccharide-induced inflammatory responses in BV2 microglia through inhibiting the TLR4-mediated NF-κB pathway.
Sign Up to like & getrecommendations! Published in 2019 at "General physiology and biophysics"
DOI: 10.4149/gpb-2018044
Abstract: Catalpol, an iridoid glucoside mainly found in the root of Rehmannia glutinosa Libosch, is known to possess various pharmacological effects. Here, we investigated its inhibitory potential against inflammatory responses in lipopolysaccharide (LPS)-stimulated BV2 microglia. Our… read more here.
Keywords: inflammatory responses; lps induced; lps; catalpol attenuates ... See more keywords