Genipin Inhibits LPS-Induced Inflammatory Response in BV2 Microglial Cells
Sign Up to like & getrecommendations! Published in 2017 at "Neurochemical Research"
DOI: 10.1007/s11064-017-2289-6
Abstract: Genipin, an aglycon of geniposide, has been reported to have anti-inflammatory effect. However, the anti-inflammatory activity of genipin on LPS-stimulated BV2 microglial cells has not been reported. In this study, we investigated the molecular mechanisms… read more here.
Keywords: genipin; lps induced; bv2 microglial; inflammatory response ... See more keywords
Anti-neuroinflammatory effects of tryptanthrin from Polygonum tinctorium Lour. in lipopolysaccharide-stimulated BV2 microglial cells
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Pharmacal Research"
DOI: 10.1007/s12272-018-1020-8
Abstract: This study was conducted to isolate the anti-neuroinflammatory component(s) in the 80% EtOH extract of P. tinctoria, and to investigate underlying molecular mechanism of the anti-neuroinflammatory component(s) in LPS-induced BV2 microglial cells. To isolate the… read more here.
Keywords: bv2 microglial; stimulated bv2; neuroinflammatory effects; anti neuroinflammatory ... See more keywords
Inhibition of inflammatory mediators and cell migration by 1,2,3,4-tetrahydroquinoline derivatives in LPS-stimulated BV2 microglial cells via suppression of NF-κB and JNK pathway.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106231
Abstract: Novel 1,2,3,4-tetrahydroquinoline derivatives with N-alkanoyl, N-benzoyl, or chlorobenzoyl substituents were designed and synthesized to inhibit nuclear factor-kappa B (NF-κB) known to be involved in the regulation of many immune and inflammatory responses. These compounds have… read more here.
Keywords: tetrahydroquinoline derivatives; mediators cell; cell migration; inflammatory mediators ... See more keywords
Antioxidant and Antineuroinflammatory Mechanisms of Kaempferol-3-O-β-d-Glucuronate on Lipopolysaccharide-Stimulated BV2 Microglial Cells through the Nrf2/HO-1 Signaling Cascade and MAPK/NF-κB Pathway
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c06916
Abstract: Aglycone- and glycoside-derived forms of flavonoids exist broadly in plants and foods such as fruits, vegetables, and peanuts. However, most studies focus on the bioavailability of flavonoid aglycone rather than its glycosylated form. Kaempferol-3-O-β-d-glucuronate (K3G)… read more here.
Keywords: microglial cells; stimulated bv2; nrf2 signaling; antioxidant antineuroinflammatory ... See more keywords
Investigations into the Role of Metabolism in the Inflammatory Response of BV2 Microglial Cells
Sign Up to like & getrecommendations! Published in 2021 at "Antioxidants"
DOI: 10.3390/antiox10010109
Abstract: Although the hallmarks of Alzheimer’s disease (AD) are amyloid beta plaques and neurofibrillary tangles, there is growing evidence that neuroinflammation, mitochondrial dysfunction and oxidative stress play important roles in disease development and progression. A major… read more here.
Keywords: metabolism inflammatory; bv2 microglial; carbon sources; microglial cells ... See more keywords
Turmeric Extract (Curcuma longa) Mediates Anti-Oxidative Effects by Reduction of Nitric Oxide, iNOS Protein-, and mRNA-Synthesis in BV2 Microglial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27030784
Abstract: Plant-derived products have been used since the beginnings of human history to treat various pathological conditions. Practical experience as well as a growing body of research suggests the benefits of the use of turmeric (Curcuma… read more here.
Keywords: protein mrna; curcuma; curcuma longa; bv2 microglial ... See more keywords