Articles with "bxd strains" as a keyword



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Analysis of electrocardiography parameters in BXD strains and quantitative trait loci for arrhythmia disorders in the mouse BXD family

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Published in 2023 at "Physiology"

DOI: 10.1152/physiol.2023.38.s1.5730564

Abstract: Introduction: Heart rhythm disorders or cardiac arrhythmias can cause sudden death and heart failure. Risk factors for cardiac arrhythmias vary including genetics, age, and other environmental and lifestyle factors. To sought how genetic background affects… read more here.

Keywords: loci; bxd strains; physiology; bxd family ... See more keywords

Echocardiography phenotyping in murine genetic reference population of BXD strains reveals significant eQTLs associated with cardiac function and morphology.

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Published in 2022 at "Physiological genomics"

DOI: 10.1152/physiolgenomics.00120.2022

Abstract: BACKGROUND The genetic reference population of recombinant inbred BXD mice has been derived from crosses between C57BL/6J and DBA/2J strains. The DBA/2J parent exhibits cardiomyopathy phenotypes, while C57BL/6J has normal heart. BXD mice are sequenced… read more here.

Keywords: bxd strains; significant eqtls; genetic reference; reference population ... See more keywords