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   Articles with "bxpc" as a keyword



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USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.

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recommendations! Published in 2023 at "Cell biology international"

DOI: 10.1002/cbin.12024

Abstract: Ubiquitin-specific protease 33 (USP33) has been implicated in various cancers, but its biological function and mechanism of action remain unknown in pancreatic cancer (PCa) as a deubiquitinating enzyme. Herein, we report that USP33 silencing inhibits… read more here.

Keywords: cell; bxpc; pca; sw1990 ... See more keywords
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Abstract 2540: Modulation of apoptosis in pancreatic adenocarcinoma BxPC-3 cells and ductal carcinoma PANC-1 cells by aqueous extract of Bryophyllum pinnatum

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recommendations! Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-2540

Abstract: Bryophyllum pinnatum (BP) has been widely used in tropical regions as traditional medicine. It is reported to have antioxidant, immunomodulatory, antidiabetic, anti-inflammatory, antihypertensive, wound healing, cytotoxic, and antitumor-promoting activities. Its major secondary metabolites include bufadienolides,… read more here.

Keywords: apoptosis; bxpc; panc cells; adenocarcinoma ... See more keywords
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The overexpression of cytochrome c oxidase subunit 6C activated by Kras mutation is related to energy metabolism in pancreatic cancer

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recommendations! Published in 2018 at "Translational cancer research"

DOI: 10.21037/19963

Abstract: Background: Kras mutation is frequently detected in pancreatic cancers and leads to altered energy metabolite. Here we investigated molecule markers related with Kras mutation, which could be used as developing new target for Kras mutant… read more here.

Keywords: bxpc; cox6c; kras mutation; pancreatic cancer ... See more keywords
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Hydroxychloroquine Promotes Bcl-xL Inhibition-induced Apoptosis in BxPC-3 Human Pancreatic Cancer Cells

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recommendations! Published in 2022 at "AntiCancer Research"

DOI: 10.21873/anticanres.15836

Abstract: Background/Aim: Anti-apoptotic proteins, including Bcl-2 and Bcl-xL, hinder cancer treatment, and several drugs targeting these molecules have been developed. One is ABT-263 (navitoclax), which targets Bcl-2, Bcl-xL, and Bcl-w. On the other hand, hydroxychloroquine (HCQ)… read more here.

Keywords: abt 263; bxpc; hcq abt; hcq ... See more keywords