PO-448 The AP-1 trancriptional complex regulates AXL-induced resistance to PI3K pathway inhibition in head and neck and esophageal cancer
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DOI: 10.1136/esmoopen-2018-eacr25.959
Abstract: Introduction Phosphoinositide-3-kinase (PI3K) pathway is often hyper activated in Head and Neck and Esopgageal squamous cell carcinoma leading to tumour cell proliferation and survival. Inhibition of the PI3K pathway using the isoform specific inhibitor BYL719,… read more here.
Keywords: byl719; axl; inhibition; resistance ... See more keywords