Improved Anticancer Photothermal Therapy Using the Bystander Effect Enhanced by Antiarrhythmic Peptide Conjugated Dopamine‐Modified Reduced Graphene Oxide Nanocomposite
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201600804
Abstract: &NA; Despite tremendous efforts toward developing novel near‐infrared (NIR)‐absorbing nanomaterials, improvement in therapeutic efficiency remains a formidable challenge in photothermal cancer therapy. This study aims to synthesize a specific peptide conjugated polydopamine‐modified reduced graphene oxide… read more here.
Keywords: effect; pda rgo; cancer; bystander effect ... See more keywords
Bystander effect of antibody–drug conjugates: fact or fiction?
Sign Up to like & getrecommendations! Published in 2022 at "Current Oncology Reports"
DOI: 10.1007/s11912-022-01266-4
Abstract: Summarizing the current preclinical and clinical evidence about bystander effect of antibody–drug conjugates (ADCs) in solid tumors. One of the main challenges of treating solid tumors with ADCs is the heterogeneous expression of the target… read more here.
Keywords: drug conjugates; bystander; effect antibody; antibody drug ... See more keywords
Investigation of Presence and Impact of Radiation-Induced Bystander Effect in Acheta domesticus.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of radiation biology"
DOI: 10.1080/09553002.2023.2188977
Abstract: PurposeRadiation-induced bystander effect (RIBE), a non-targeted effect of ionizing radiation in which non-irradiated individuals behave as if they have been irradiated after interactions with irradiated individuals, has been well documented in vertebrates. However, little research… read more here.
Keywords: impacts ribe; insects; induced bystander; bystander effect ... See more keywords
Dolaflexin: A Novel Antibody–Drug Conjugate Platform Featuring High Drug Loading and a Controlled Bystander Effect
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.mct-20-0166
Abstract: After significant effort over the last 30 years, antibody–drug conjugates (ADC) have recently gained momentum as a therapeutic modality, and nine ADCs have been approved by the FDA to date, with additional ADCs in late… read more here.
Keywords: drug; bystander effect; antibody drug; dolaflexin ... See more keywords
Radiation-induced bystander effect and its clinical implications
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1124412
Abstract: For many years, targeted DNA damage caused by radiation has been considered the main cause of various biological effects. Based on this paradigm, any small amount of radiation is harmful to the organism. Epidemiological studies… read more here.
Keywords: effect; bystander effect; radiation; low dose ... See more keywords
Prosocial priming and bystander effect in an online context
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychology"
DOI: 10.3389/fpsyg.2022.945630
Abstract: The present study tested the effect of priming the concept of prosociality on the bystander effect in an online environment. Participants were sent an e-mail requesting a plea for help and randomly assigned to one… read more here.
Keywords: effect; effect online; bystander effect; priming bystander ... See more keywords
Golgi Phosphoprotein 3 Mediates Radiation-Induced Bystander Effect via ERK/EGR1/TNF-α Signal Axis
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DOI: 10.3390/antiox11112172
Abstract: The radiation-induced bystander effect (RIBE), an important non-targeted effect of radiation, has been proposed to be associated with irradiation-caused secondary cancers and reproductive damage beyond the irradiation-treated area after radiotherapy. However, the mechanisms for RIBE… read more here.
Keywords: effect; signal axis; induced bystander; bystander effect ... See more keywords
Ginsenoside Rh2 Ameliorates Doxorubicin-Induced Senescence Bystander Effect in Breast Carcinoma Cell MDA-MB-231 and Normal Epithelial Cell MCF-10A
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20051244
Abstract: The anthracycline antibiotic doxorubicin is commonly used antineoplastic drug in breast cancer treatment. Like most chemotherapy, doxorubicin does not selectively target tumorigenic cells with high proliferation rate and often causes serve side effects. In the… read more here.
Keywords: mcf 10a; mda 231; breast; senescence ... See more keywords
Radiation-Induced Bystander Effect Mediated by Exosomes Involves the Replication Stress in Recipient Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23084169
Abstract: Exosomes released by irradiated cells mediate the radiation-induced bystander effect, which is manifested by DNA breaks detected in recipient cells; yet, the specific mechanism responsible for the generation of chromosome lesions remains unclear. In this… read more here.
Keywords: stress; replication; recipient cells; irradiated cells ... See more keywords