Articles with "c01 c04" as a keyword



Preclinical assessment of two FcγRI-specific antibodies that competitively inhibit immune complex-FcγRI binding to suppress autoimmune responses

Sign Up to like & get
recommendations!
Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-65133-z

Abstract: Overactivation of FcγRI by immune complexes (IC) is implicated in various autoimmune disorders and neuropathies. Currently, no effective FcγRI-specific blocking antibodies are available. Here we report preclinical data revealing two anti-FcγRI antibodies, C01 and C04,… read more here.

Keywords: immune complex; c01 c04; autoimmune; assessment two ... See more keywords