Non‐canonical bivalent H3K4me3K9me3 recognition by Spindlin1/C11orf84 complex
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202100229
Abstract: Bivalent chromatin with active H3K4me3 and repressive H3K27me3 was initially identified in embryonic stem cells (ESCs) to poise expression of developmental genes upon lineage commitment. Since then, many more different bivalent modifications have been demonstrated… read more here.
Keywords: spindlin1 c11orf84; non canonical; bivalent; c11orf84 complex ... See more keywords
Structural mechanism of bivalent histone H3K4me3K9me3 recognition by the Spindlin1/C11orf84 complex in rRNA transcription activation
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-21236-x
Abstract: Spindlin1 is a unique multivalent epigenetic reader that facilitates ribosomal RNA transcription. In this study, we provide molecular and structural basis by which Spindlin1 acts in complex with C11orf84 to preferentially recognize non-canonical bivalent mark… read more here.
Keywords: transcription; c11orf84 complex; c11orf84; spindlin1 c11orf84 ... See more keywords