Articles with "c12orf49" as a keyword



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POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation

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Published in 2020 at "Protein & Cell"

DOI: 10.1007/s13238-020-00753-3

Abstract: Sterol-regulatory element binding proteins (SREBPs) are the key transcriptional regulators of lipid metabolism. The activation of SREBP requires translocation of the SREBP precursor from the endoplasmic reticulum to the Golgi, where it is sequentially cleaved… read more here.

Keywords: protease; srebp; site protease; c12orf49 ... See more keywords