Functional Expression and Construction of a Self‐Sufficient Cytochrome P450 Chimera for Efficient Steroidal C14α Hydroxylation in Escherichia coli
Sign Up to like & getrecommendations! Published in 2024 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28911
Abstract: C14‐functionalized steroids enabled diverse biological activities in anti‐gonadotropin and anticancer therapy. However, access to C14‐functionalized steroids was impeded by the deficiency of chemical synthetic methods. Recently, several membrane‐bound fungal cytochrome P450s (CYPs) have been identified… read more here.
Keywords: escherichia coli; c14 hydroxylation; steroidal c14; c14 ... See more keywords
Myristic acid induces proteomic and secretomic changes associated with steatosis, cytoskeleton remodeling, endoplasmic reticulum stress, protein turnover and exosome release in HepG2 cells.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2018.04.008
Abstract: Myristic acid, the 14-carbon saturated fatty acid (C14:0), is associated to an increased cardiovascular disease risk. Since it is found in low concentration in cells, its specific properties have not been fully analyzed. The aim… read more here.
Keywords: myristic acid; c14; hepg2 cells; proteomic secretomic ... See more keywords
Cellular membrane-targeting ruthenium complexes as efficient photosensitizers for broad-spectrum antibacterial activity.
Sign Up to like & getrecommendations! Published in 2023 at "Dalton transactions"
DOI: 10.1039/d3dt01001e
Abstract: A ruthenium complex [Ru(phen)2(phen-5-amine)-C14] (Ru-C14) with broad-spectrum antibacterial activity was designed and synthesized; positively charged Ru-C14 could target bacteria via electrostatic interactions and showed high binding effectiveness to cell membranes. In addition, Ru-C14 could act… read more here.
Keywords: c14; antibacterial activity; membrane targeting; spectrum antibacterial ... See more keywords
Greatly increased electrical conductivity of PBTTT-C14 thin film via controllable single precursor vapor phase infiltration
Sign Up to like & getrecommendations! Published in 2022 at "Nanotechnology"
DOI: 10.1088/1361-6528/ac96fa
Abstract: Doping is an important strategy for effectively regulating the charge carrier concentration of semiconducting materials. In this study, the electronic properties of organic–inorganic hybrid semiconducting polymers, synthesized via in situ controlled vapor phase infiltration (VPI)… read more here.
Keywords: infiltration; c14; pbttt c14; vapor phase ... See more keywords
Efficiently tuning the electrical performance of PBTTT-C14 thin film via in situ controllable multiple precursors (Al2O3:ZnO) vapor phase infiltration
Sign Up to like & getrecommendations! Published in 2024 at "Nanotechnology"
DOI: 10.1088/1361-6528/ad375c
Abstract: Conjugated polymer-based organic/inorganic hybrid materials become the current research frontier and show great potential to integrate flexible polymers and rigid solid materials, which have been widely used in the field of various flexible electronics and… read more here.
Keywords: c14 thin; pbttt c14; thin film; c14 ... See more keywords
New Ratios for Performance Improvement for Identifying Acyl-CoA Dehydrogenase Deficiencies in Expanded Newborn Screening: A Retrospective Study
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2019.00811
Abstract: Some success in identifying acyl-CoA dehydrogenase (ACAD) deficiencies before they are symptomatic has been achieved through tandem mass spectrometry. However, there has been several challenges that need to be confronted, including excess false positives, the… read more here.
Keywords: coa dehydrogenase; c14; new ratios; acyl coa ... See more keywords
AFM Study of Nanoscale Membrane Perturbation Induced by Antimicrobial Lipopeptide C14 KYR
Sign Up to like & getrecommendations! Published in 2021 at "Membranes"
DOI: 10.3390/membranes11070495
Abstract: Lipopeptides have been extensively studied as potential antimicrobial agents. In this study, we focused on the C14-KYR lipopeptide, a modified version of the KYR tripeptide with myristic acid at the N-terminus. Here, membrane perturbation of… read more here.
Keywords: c14; c14 kyr; membrane perturbation;