Improvement of Lipoplexes With a Sialic Acid Mimetic to Target the C1858T PTPN22 Variant for Immunotherapy in Endocrine Autoimmunity
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DOI: 10.3389/fimmu.2022.838331
Abstract: The C1858T variant of the protein tyrosine phosphatase N22 (PTPN22) gene is associated with pathophysiological phenotypes in several autoimmune conditions, namely, Type 1 diabetes and autoimmune thyroiditis. The R620W variant protein, encoded by C1858T, leads… read more here.
Keywords: c1858t ptpn22; liposirna sig10l; ptpn22; c1858t ... See more keywords