Down-Regulation of C1GALT1 Enhances the Progression of Cholangiocarcinoma through Activation of AKT/ERK Signaling Pathways
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DOI: 10.3390/life12020174
Abstract: Alteration of mucin-type O-glycosylation is implicated in tumor progression and metastasis of cholangiocarcinoma (CCA). Core 1 β1-3 Galactosyltransferase (C1GALT1) is a primary enzyme that regulates the elongation of core 1-derived mucin-type O-glycans. Dysregulation of C1GALT1… read more here.
Keywords: core; cca; akt erk; c1galt1 ... See more keywords
Update on the role of C1GALT1 in cancer
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DOI: 10.3892/ol.2022.13217
Abstract: Cancer remains one of the most difficult diseases to treat. In the quest for early diagnoses to improve patient survival and prognosis, targeted therapies have become a hot research topic in recent years. Glycosylation is… read more here.
Keywords: update role; c1galt1 cancer; role c1galt1; cancer ... See more keywords