OR16 Donor-specific antibodies (DSA) detected by C1Q and C3D assays predict antibody-mediated rejection (AMR) in renal transplant (TX) patients, but specific detection of IGG2, IGG3, IGG4, IGA, and IGM DSA, and ANTI-AT1R and anti-etar antibodies do not
Sign Up to like & getrecommendations! Published in 2017 at "Human Immunology"
DOI: 10.1016/j.humimm.2017.06.022
Abstract: Aim To investigate the specific roles for Class I and Class II DSA, complement binding and activation, and non-HLA antibodies, in renal tx patients with AMR. Methods One Lambda®: LABScreen™ (routine total IgG and modified… read more here.
Keywords: detection; class; dsa; igg2 igg3 ... See more keywords
The disappointing contribution of anti-human leukocyte antigen donor-specific antibodies characteristics for predicting allograft loss
Sign Up to like & getrecommendations! Published in 2018 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfy088
Abstract: Background Pathogenicity of donor-specific antibodies (DSAs) can be assessed using the single-antigen flow beads (SAFB) assays through mean fluorescence intensity (MFI) with or without serum ethylenediaminetetraacetic acid (EDTA) treatment, measurement of C1q or C3d binding… read more here.
Keywords: specific antibodies; donor specific; c1q c3d; loss ... See more keywords