Complement component 1q subcomponent binding protein in the brain of the rat
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-40788-z
Abstract: Complement component 1q subcomponent binding protein (C1qbp) is a multifunctional protein involved in immune response, energy homeostasis of cells as a plasma membrane receptor, and a nuclear, cytoplasmic or mitochondrial protein. Recent reports suggested its… read more here.
Keywords: protein; microscopy; complement component; brain ... See more keywords
Complement C1q binding protein regulates T cells’ mitochondrial fitness to affect their survival, proliferation, and anti–tumor immune function
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Science"
DOI: 10.1111/cas.15261
Abstract: T cells survival, proliferation, and anti–tumor response are closely linked to their mitochondrial health. Complement C1q binding protein (C1QBP) promotes mitochondrial fitness through regulation of mitochondrial metabolism and morphology. However, whether C1QBP regulates T cell… read more here.
Keywords: c1qbp; anti tumor; proliferation; tumor ... See more keywords
Circular RNA MTCL1 promotes advanced laryngeal squamous cell carcinoma progression by inhibiting C1QBP ubiquitin degradation and mediating beta-catenin activation
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Cancer"
DOI: 10.1186/s12943-022-01570-4
Abstract: Background Circular RNAs (circRNAs) are involved in regulatory processes of ubiquitination and deubiquitination in various tumors at post-transcriptional epigenetic modification level. However, the underlying mechanism and its biological functions of circRNAs in the advanced laryngeal… read more here.
Keywords: c1qbp; catenin; ubiquitin degradation; carcinoma ... See more keywords
AB094. C1QBP negatively regulates the activation of oncoprotein YBX1 in the renal cell carcinoma as revealed by interactomics analysis
Sign Up to like & getrecommendations! Published in 2017 at "Translational Andrology and Urology"
DOI: 10.21037/tau.2017.s094
Abstract: Background The Y-box-binding protein 1 (YBX1) plays a critical role in tumorigenesis by promoting cell proliferation, overriding cell cycle check points, and enhancing genomic instability. Methods The interactome of YBX1 in renal cell carcinoma (RCC)… read more here.
Keywords: renal cell; ybx1 renal; carcinoma; ybx1 ... See more keywords
Hypoxia-Mediated Complement 1q Binding Protein Regulates Metastasis and Chemoresistance in Triple-Negative Breast Cancer and Modulates the PKC-NF-κB-VCAM-1 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.607142
Abstract: Objectives Complement 1q binding protein (C1QBP/HABP1/p32/gC1qR) has been found to be overexpressed in triple-negative breast cancer (TNBC). However, the underlying mechanisms of high C1QBP expression and its role in TNBC remain largely unclear. Hypoxia is… read more here.
Keywords: chemoresistance; metastasis; tnbc; expression ... See more keywords
C1QBP regulates mitochondrial plasticity to impact tumor progression and antitumor immune response
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.1012112
Abstract: Mitochondrial plasticity including mitochondrial dynamics, metabolic flexibility, and mitochondrial quality control, impact tumor cells’ progression and determine immune cells’ fate. Complement C1q binding protein (C1QBP) plays an indispensable role through regulating mitochondrial morphology, metabolism, and… read more here.
Keywords: c1qbp; mitochondrial plasticity; impact tumor; plasticity impact ... See more keywords
C1QBP regulates apoptosis of renal cell carcinoma via modulating xanthine dehydrogenase (XDH) mediated ROS generation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Medical Sciences"
DOI: 10.7150/ijms.71703
Abstract: Background: Complement component 1 Q subcomponent binding protein (C1QBP) plays a vital role in the progression and metabolism of cancer. Studies have shown that xanthine dehydrogenase (XDH)-derived reactive oxygen species (ROS) accelerates tumor growth, and… read more here.
Keywords: c1qbp; renal cell; xanthine dehydrogenase; apoptosis renal ... See more keywords
The Mitochondrial Protein C1QBP Promotes Hepatocellular Carcinoma Progression by Enhancing Cell Survival, Migration and Invasion
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cancer"
DOI: 10.7150/jca.69379
Abstract: Backgrounds: Hepatocellular carcinoma (HCC) is a major type of death-causing cancer whose pathological mechanisms are not fully understood. In addition, the identification of effective biomarkers for HCC prognosis is in emergency. Although a variety of… read more here.
Keywords: c1qbp; migration invasion; hcc; hepatocellular carcinoma ... See more keywords